Abstract
Antimicrobial resistance (AMR) resembles one of the worldwide alarming threats to human health nowadays. It is classified as one of the top 10 global health concerns facing humankind according to the World Health Organization (WHO). Drug-resistant infections are mostly brought on by the improper use and overuse of antibiotics. As antibiotics lose effectiveness over time, urgent multisectoral action is needed to fulfill the Sustainable Development Goals (SDGs). Superior antibacterial action against pathogenic microorganisms can be found in metal-based nanoparticles including copper, gold, and silver. Metal nanoparticles are being looked at by scientists and researchers as a potential therapeutic agent.The non – specific bacterial toxicity mechanisms of metal nanoparticles due to their small size and capacity to influence several macromolecules within the bacterial cell simultaneously, make it challenging for bacteria to acquire resistance and widen the range of antibacterial activity. Furthermore, that makes the metal nanoparticles an attractive alternative to conventional antibiotics. While both chemical and biological methods can be used to generate metal nanoparticles, by utilizing the yeast Saccharomyces cerevisiae, we have pioneered a revolutionary green method to generate metal nanoparticles. This green strategy is sustainable, simple to operate, and is cost – effective.
| Date of Award | Apr 2023 |
|---|---|
| Original language | American English |
| Supervisor | David Sheehan (Supervisor) |
Keywords
- Antimicrobial Resistance (AMR)
- World Health Organization (WHO)
- Metal nanoparticles
- Silver nanoparticles
- Green synthesis
- Chemical synthesis