3D printing process is computerized, allowing each level of the printed part to be fully controlled in situ for producing the desired dressings. In this thesis project, a new re-entrant-based auxetic shape was designed and 3D printed using Digital Light Processing (DLP). The printed bandage has glucose and pH biosensors integrated into the matrix of the wound dressings. The chemical characteristics of the biosensors were comprehensively discussed. The first experiment of the 3D printed re-entrant auxetic hydrogel wound dressing, doped with pH indicator phenol red dye, was developed and mechanically characterized. The re-entrant auxetic design allows the wound dressings'' to adhere to complex body parts, such as joints on arms and legs. The mechanical testing of the auxetic structure has shown a yield strength of 140 kPa and Young's modulus of 78 MPa. Also, the printed wound dressing has a swelling capacity of up to 14%, limited weight loss to 3% in six days, and porosity of nearly 1.2%. Further, a second experiment was conducted with paper-based glucose and pH colorimetric sensors. They were attached on the 3D-printed auxetic hydrogel surface, and they monitored the wound status by detecting pH levels and glucose concentration changes. The paper-based sensors are profoundly cost-effective and are found to be capable of monitoring the wound's conditions. Also, the dressing's adhesion mechanism was analyzed, and the primary printing parameters were optimized. The results confirmed that high concentrations of PAA solutions could enhance the adhesion capability. Fundamental challenges of the 3D printing process during the lab experiment and future recommendations are highlighted.
Date of Award | Dec 2022 |
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Original language | American English |
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- wound dressings
- 3D printing
- sensor-integrated bandages
- glucose sensors
- pH sensors
- auxetic structures
3D Printing Hydrogel Based Smart Patches for Wounds
Tsegay, F. (Author). Dec 2022
Student thesis: Master's Thesis