Variations in the accuracy of the ECG based detection of obstructive sleep apnoea (OSA) for different numbers of ECG leads and categories of OSA events

Kris Nilsen, Eugene Zilberg, David Burton, Ahsan H. Khandoker, Marimuthu Palaniswami

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

4 Scopus citations

Abstract

This study investigates the finding that there is a more pronounced change to ECG physiological predictors during apnoea events compared to hypopnoea events and therefore accurate detection of hypopnoea events is likely to be more challenging than detection of apnoea events. The relevant statistical analysis was conducted by generating logistic regression models from the two data sets: the first one containing only the apnoea events and controls and the second data set containing only the hypopnoea events and controls. The discriminating ability of the model from the apnoea data set (AUC = 0.903, CI = 0.888-0.920) was significantly superior compared to the model from the hypopnoea data set (AUC = 0.842, CI = 0.817-0.866). The second study objective investigated whether regression models comprising the OSA predictors derived from the two ECG signals performed better than models that involved parameters of a single ECG. The optimised two signal ECG model (AUC = 0.878 and CI = 0.864-0.893) outperformed the best single ECG model (AUC = 0.843, CI = 0.826-0.860), suggesting that improved results can be achieved using an additional ECG lead.

Original languageBritish English
Title of host publicationProceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
PublisherIEEE Computer Society
Pages3492-3495
Number of pages4
ISBN (Print)9781424418152
DOIs
StatePublished - 2008
Event30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - Vancouver, BC, Canada
Duration: 20 Aug 200825 Aug 2008

Publication series

NameProceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology"

Conference

Conference30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
Country/TerritoryCanada
CityVancouver, BC
Period20/08/0825/08/08

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