TY - JOUR
T1 - Vanadium as potential therapeutic agent for COVID-19
T2 - A focus on its antiviral, antiinflamatory, and antihyperglycemic effects
AU - Semiz, Sabina
N1 - Funding Information:
Not applicable.
Publisher Copyright:
© 2021 The Author(s)
PY - 2022/1
Y1 - 2022/1
N2 - An increasing evidence suggests that vanadium compounds are novel potential drugs in the treatment of diabetes, atherosclerosis, and cancer. Vanadium has also demonstrated activities against RNA viruses and is a promising candidate for treating acute respiratory diseases. The antidiabetic, antihypertensive, lipid-lowering, cardioprotective, antineoplastic, antiviral, and other potential effects of vanadium are summarized here. Given the beneficial antihyperglycemic and antiinflammatory effects as well as the potential mechanistic link between the COVID-19 and diabetes, vanadium compounds could be considered as a complement to the prescribed treatment of COVID-19. Thus, further clinical trials are warranted to confirm these favorable effects of vanadium treatment in COVID-19 patients, which appear not to be studied yet.
AB - An increasing evidence suggests that vanadium compounds are novel potential drugs in the treatment of diabetes, atherosclerosis, and cancer. Vanadium has also demonstrated activities against RNA viruses and is a promising candidate for treating acute respiratory diseases. The antidiabetic, antihypertensive, lipid-lowering, cardioprotective, antineoplastic, antiviral, and other potential effects of vanadium are summarized here. Given the beneficial antihyperglycemic and antiinflammatory effects as well as the potential mechanistic link between the COVID-19 and diabetes, vanadium compounds could be considered as a complement to the prescribed treatment of COVID-19. Thus, further clinical trials are warranted to confirm these favorable effects of vanadium treatment in COVID-19 patients, which appear not to be studied yet.
KW - COVID-19
KW - Diabetes mellitus
KW - Hyperglycemia
KW - Inflammation
KW - Insulin sensitivity
KW - SARS-CoV-2 coronavirus
KW - Vanadium
UR - http://www.scopus.com/inward/record.url?scp=85119067496&partnerID=8YFLogxK
U2 - 10.1016/j.jtemb.2021.126887
DO - 10.1016/j.jtemb.2021.126887
M3 - Review article
C2 - 34798510
AN - SCOPUS:85119067496
SN - 0946-672X
VL - 69
JO - Journal of Trace Elements in Medicine and Biology
JF - Journal of Trace Elements in Medicine and Biology
M1 - 126887
ER -
