Ultrasound-assisted liquid biphasic system

Shir Reen Chia; Albert Fu Xian Lim; Kit Wayne Chew; Pau Loke Show

doi:10.1016/B978-0-12-819986-2.00009-8

Ultrasound-assisted liquid biphasic system

Shir Reen Chia, Albert Fu Xian Lim, Kit Wayne Chew, Pau Loke Show

Chemical and Petroleum Engineering

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

An integrated method of cell disruption with primary separation is discussed in this chapter. Ultrasound-assisted liquid biphasic systems (UA-LBSs) are an integrated method with adjustable parameters, including the phase forming components, conditions of ultrasound, processing time and more. The basic working principle of UA-LBSs are highlighted with their major applications. UA-LBSs are mostly used in pretreating and extracting materials or components, as they integrate gentle cell disruption method with effective separation technique for short processing time, lower volume of solvent required, and reduced cost for overall process. The efficiency of the system is susceptible to changes in the operating parameters and targeted compounds. The advantages and limitations of this technique, as well as the potential for scaling up the system, are also discussed in this chapter. It is seen to be a promising technology for both laboratory- and industrial-scale applications.

Original language	British English
Title of host publication	Liquid Biphasic System
Subtitle of host publication	Fundamentals and Applications in Bioseparation Technology
Publisher	Elsevier
Pages	149-166
Number of pages	18
ISBN (Electronic)	9780128199862
DOIs	https://doi.org/10.1016/B978-0-12-819986-2.00009-8
State	Published - 1 Jan 2020

Keywords

Cell disruption
Extraction
Liquid Biphasic System
Purification
Ultrasound-assisted

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10.1016/B978-0-12-819986-2.00009-8

Cite this

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abstract = "An integrated method of cell disruption with primary separation is discussed in this chapter. Ultrasound-assisted liquid biphasic systems (UA-LBSs) are an integrated method with adjustable parameters, including the phase forming components, conditions of ultrasound, processing time and more. The basic working principle of UA-LBSs are highlighted with their major applications. UA-LBSs are mostly used in pretreating and extracting materials or components, as they integrate gentle cell disruption method with effective separation technique for short processing time, lower volume of solvent required, and reduced cost for overall process. The efficiency of the system is susceptible to changes in the operating parameters and targeted compounds. The advantages and limitations of this technique, as well as the potential for scaling up the system, are also discussed in this chapter. It is seen to be a promising technology for both laboratory- and industrial-scale applications.",

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Ultrasound-assisted liquid biphasic system

Abstract

Keywords

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