Thermal effect on a viscously-deformed liposome in a laser trap

K. K. Liu, J. J. Foo, Vincent Chan

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

By combining optical tweezers with temperature control chamber, the viscous drag and mechanical deformation of a single liposome under flow during the phase transition of lipid bilayer is elucidated. It is found that the deformability D+12 of vesicle increases with the increase of temperature at physiological flow velocity during sample heating, and almost remains constant during sample cooling. Overall, this study provides new insights into coupling thermal and hydrodynamics effect on model membrane vesicle in physiological flow systems.

Original languageBritish English
Title of host publicationProceedings of the IEEE-EMBS Special Topic Conference on Molecular, Cellular and Tissue Engineering, MCTE 2002
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages77-78
Number of pages2
ISBN (Electronic)0780375572, 9780780375574
DOIs
StatePublished - 2002
EventIEEE-EMBS Special Topic Conference on Molecular, Cellular and Tissue Engineering, MCTE 2002 - Genoa, Italy
Duration: 6 Jun 20029 Jun 2002

Publication series

NameProceedings of the IEEE-EMBS Special Topic Conference on Molecular, Cellular and Tissue Engineering, MCTE 2002

Conference

ConferenceIEEE-EMBS Special Topic Conference on Molecular, Cellular and Tissue Engineering, MCTE 2002
Country/TerritoryItaly
CityGenoa
Period6/06/029/06/02

Keywords

  • Deformation
  • Hydrodynamics flow
  • Optical tweezers
  • Temperature effect

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