The three-substituted indolinone cyclin-dependent kinase 2 inhibitor 3-[1-(3H-imidazol-4-yl)-meth-(Z)-ylidene]-5-methoxy-1,3-dihydro-indol-2-one (SU9516) kills human leukemia cells via down-regulation of Mcl-1 through a transcriptional mechanism

Ning Gao, Lora Kramer, Mohamed Rahmani, Paul Dent, Steven Grant

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Pharmacology, Toxicology and Pharmaceutical Science