@inproceedings{f1b1a52b0ffa47ccb0e5725de51aedde,
title = "The influence of pharmacological autonomic blockades on multi-scale measures of heart rate variability",
abstract = "Multi-scale measures have been used extensively to characterize non-linear dynamics of heart beats. However a physiological interpretation of the exponents associated with various scales of these measures and the role of the sympathetic and parasympathetic activities have not been attempted. In this study three multi-scale measures were compared at different scales in a pharmacological autonomic blockade experiment, starting with a control phase. It was then followed by injection of propranolol causing sympathetic blockade and injection of atropine resulting in the blockade of both sympathetic and parasympathetic pathways. Multiscale Entropy (MSE), Multi Fractal Detrended Fluctuation Analysis (MFDFA) and Renyi Entropy (RE) were compared using a paired test statistics. The measures performed differently depending on the scale factors and RE showed the best results indicating a good discrimination particularly at higher scale exponents. This study provides a basis for understanding the effect of autonomic activity on multi-scale measures with respect to changes in parasympathetic and sympathetic activity.",
keywords = "Autonomic Blockades, Autonomic Nervous System, Entropy, Heart Rate Variability, Multi-Scale",
author = "Faezeh Marzbanrad and Karmakar, {C. K.} and Khandoker, {A. H.} and M. Palaniswami and T. Moritani and Jelinek, {H. F.}",
note = "Publisher Copyright: {\textcopyright} Springer Nature Singapore Pte Ltd. 2018.; Joint Conference of the European Medical and Biological Engineering Conference, EMBEC 2017 and Nordic-Baltic Conference on Biomedical Engineering and Medical Physics, NBC 2107 ; Conference date: 11-06-2017 Through 15-06-2017",
year = "2017",
doi = "10.1007/978-981-10-5122-7_116",
language = "British English",
isbn = "9789811051210",
series = "IFMBE Proceedings",
publisher = "Springer Verlag",
pages = "462--465",
editor = "Hannu Eskola and Outi Vaisanen and Jari Viik and Jari Hyttinen",
booktitle = "EMBEC and NBC 2017 - Joint Conference of the European Medical and Biological Engineering Conference EMBEC 2017 and the Nordic-Baltic Conference on Biomedical Engineering and Medical Physics, NBC 2017",
address = "Germany",
}