The holy grail of organocatalysis: Intermolecular α-alkylation of aldehydes

Andrea Nekane Alba; Mònica Viciano; Ramon Rios

doi:10.1002/cctc.200900196

The holy grail of organocatalysis: Intermolecular α-alkylation of aldehydes

Andrea Nekane Alba
, Mònica Viciano
, Ramon Rios

Chemistry

Universitat de Barcelona

Research output: Contribution to journal › Review article › peer-review

67 Scopus citations

Abstract

This is the cup of a chemist: Organocatalytic intermolecular a-alkylation has been accomplished. The groups of Melchiorre and Cozzi have recently reported the realization of this long-time goal in organocatalysis, by the crucial use of stabilized carbocations. Alkylated products are obtained in good yields and with moderate to good enantioselectivities.

Original language	British English
Pages (from-to)	437-439
Number of pages	3
Journal	ChemCatChem
Volume	1
Issue number	4
DOIs	https://doi.org/10.1002/cctc.200900196
State	Published - 7 Dec 2009

Keywords

Alkylation
Carbocations
Enantioselectivity
Organocatalysis
Synthetic methods

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10.1002/cctc.200900196

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abstract = "This is the cup of a chemist: Organocatalytic intermolecular a-alkylation has been accomplished. The groups of Melchiorre and Cozzi have recently reported the realization of this long-time goal in organocatalysis, by the crucial use of stabilized carbocations. Alkylated products are obtained in good yields and with moderate to good enantioselectivities.",

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AU - Rios, Ramon

PY - 2009/12/7

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AB - This is the cup of a chemist: Organocatalytic intermolecular a-alkylation has been accomplished. The groups of Melchiorre and Cozzi have recently reported the realization of this long-time goal in organocatalysis, by the crucial use of stabilized carbocations. Alkylated products are obtained in good yields and with moderate to good enantioselectivities.

KW - Alkylation

KW - Carbocations

KW - Enantioselectivity

KW - Organocatalysis

KW - Synthetic methods

UR - https://www.scopus.com/pages/publications/77954348230

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M3 - Review article

AN - SCOPUS:77954348230

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ER -

The holy grail of organocatalysis: Intermolecular α-alkylation of aldehydes

Abstract

Keywords

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