TY - JOUR
T1 - The Eurasian heartland
T2 - A continental perspective on Y-chromosome diversity
AU - Wells, R. Spencer
AU - Yuldasheva, Nadira
AU - Ruzibakiev, Ruslan
AU - Underhill, Peter A.
AU - Evseeva, Irina
AU - Blue-Smith, Jason
AU - Jin, Li
AU - Su, Bing
AU - Pitchappan, Ramasamy
AU - Shanmugalakshmi, Sadagopal
AU - Balakrishnan, Karuppiah
AU - Read, Mark
AU - Pearson, Nathaniel M.
AU - Zerjal, Tatiana
AU - Webster, Matthew T.
AU - Zholoshvili, Irakli
AU - Jamarjashvili, Elena
AU - Gambarov, Spartak
AU - Nikbin, Behrouz
AU - Dostiev, Ashur
AU - Aknazarov, Ogonazar
AU - Zalloua, Pierre
AU - Tsoy, Igor
AU - Kitaev, Mikhail
AU - Mirrakhimov, Mirsaid
AU - Chariev, Ashir
AU - Bodmer, Walter F.
PY - 2001/8/28
Y1 - 2001/8/28
N2 - The nonrecombining portion of the human Y chromosome has proven to be a valuable tool for the study of population history. The maintenance of extended haplotypes characteristic of particular geographic regions, despite extensive admixture, allows complex demographic events to be deconstructed. In this study we report the frequencies of 23 Y-chromosome biallelic polymorphism haplotypes in 1,935 men from 49 Eurasian populations, with a particular focus on Central Asia. These haplotypes reveal traces of historical migrations, and provide an insight into the earliest patterns of settlement of anatomically modern humans on the Eurasian continent. Central Asia is revealed to be an important reservoir of genetic diversity, and the source of at least three major waves of migration leading into Europe, the Americas, and India. The genetic results are interpreted in the context of Eurasian linguistic patterns.
AB - The nonrecombining portion of the human Y chromosome has proven to be a valuable tool for the study of population history. The maintenance of extended haplotypes characteristic of particular geographic regions, despite extensive admixture, allows complex demographic events to be deconstructed. In this study we report the frequencies of 23 Y-chromosome biallelic polymorphism haplotypes in 1,935 men from 49 Eurasian populations, with a particular focus on Central Asia. These haplotypes reveal traces of historical migrations, and provide an insight into the earliest patterns of settlement of anatomically modern humans on the Eurasian continent. Central Asia is revealed to be an important reservoir of genetic diversity, and the source of at least three major waves of migration leading into Europe, the Americas, and India. The genetic results are interpreted in the context of Eurasian linguistic patterns.
UR - http://www.scopus.com/inward/record.url?scp=17944364925&partnerID=8YFLogxK
U2 - 10.1073/pnas.171305098
DO - 10.1073/pnas.171305098
M3 - Article
C2 - 11526236
AN - SCOPUS:17944364925
SN - 0027-8424
VL - 98
SP - 10244
EP - 10249
JO - Proceedings of the National Academy of Sciences of the United States of America
JF - Proceedings of the National Academy of Sciences of the United States of America
IS - 18
ER -