Testicular morphology in the 47XXY fetus at 16 weeks gestation

John A. Rock; William A. Rock; Jack Rary

doi:10.1016/0020-7292(82)90052-2

Testicular morphology in the 47XXY fetus at 16 weeks gestation

John A. Rock
, William A. Rock
, Jack Rary

College of Medicine and Health Sciences

The Johns Hopkins Hospital

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

The testis from two 47XXY fetuses (20 weeks) revealed histologic features not dissimilar from that observed in a normal 46XY fetus of similar gestational age. These findings support the observation that the loss of germ cells in patients with Klinefelter's syndrome is an event which begins in infancy and not in utero and progresses through early childhood and the prepubertal period. At puberty germinal aplasia may be complete with clinical evidence of testicular atrophy.

Original language	British English
Pages (from-to)	261-263
Number of pages	3
Journal	International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
Volume	20
Issue number	4
DOIs	https://doi.org/10.1016/0020-7292(82)90052-2
State	Published - Aug 1982

Keywords

Germ cells
Germinal aplasia
Gestational age
In utero
Klinefelter's syndrome
Testis

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10.1016/0020-7292(82)90052-2

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title = "Testicular morphology in the 47XXY fetus at 16 weeks gestation",

abstract = "The testis from two 47XXY fetuses (20 weeks) revealed histologic features not dissimilar from that observed in a normal 46XY fetus of similar gestational age. These findings support the observation that the loss of germ cells in patients with Klinefelter's syndrome is an event which begins in infancy and not in utero and progresses through early childhood and the prepubertal period. At puberty germinal aplasia may be complete with clinical evidence of testicular atrophy.",

keywords = "Germ cells, Germinal aplasia, Gestational age, In utero, Klinefelter's syndrome, Testis",

author = "Rock, \{John A.\} and Rock, \{William A.\} and Jack Rary",

year = "1982",

month = aug,

doi = "10.1016/0020-7292(82)90052-2",

language = "British English",

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journal = "International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics",

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T1 - Testicular morphology in the 47XXY fetus at 16 weeks gestation

AU - Rock, John A.

AU - Rock, William A.

AU - Rary, Jack

PY - 1982/8

Y1 - 1982/8

N2 - The testis from two 47XXY fetuses (20 weeks) revealed histologic features not dissimilar from that observed in a normal 46XY fetus of similar gestational age. These findings support the observation that the loss of germ cells in patients with Klinefelter's syndrome is an event which begins in infancy and not in utero and progresses through early childhood and the prepubertal period. At puberty germinal aplasia may be complete with clinical evidence of testicular atrophy.

AB - The testis from two 47XXY fetuses (20 weeks) revealed histologic features not dissimilar from that observed in a normal 46XY fetus of similar gestational age. These findings support the observation that the loss of germ cells in patients with Klinefelter's syndrome is an event which begins in infancy and not in utero and progresses through early childhood and the prepubertal period. At puberty germinal aplasia may be complete with clinical evidence of testicular atrophy.

KW - Germ cells

KW - Germinal aplasia

KW - Gestational age

KW - In utero

KW - Klinefelter's syndrome

KW - Testis

UR - https://www.scopus.com/pages/publications/0019974073

U2 - 10.1016/0020-7292(82)90052-2

DO - 10.1016/0020-7292(82)90052-2

M3 - Article

C2 - 6127257

AN - SCOPUS:0019974073

SN - 0020-7292

VL - 20

SP - 261

EP - 263

JO - International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

JF - International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

IS - 4

ER -

Testicular morphology in the 47XXY fetus at 16 weeks gestation

Abstract

Keywords

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