Synthesis and Organization of Gold-Peptide Nanoparticles for Catalytic Activities

Manzar Abbas, Hepi Hari Susapto, Charlotte A.E. Hauser

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


A significant development in the synthesis strategies of metal-peptide composites and their applications in biomedical and bio-catalysis has been reported. However, the random aggregation of gold nanoparticles provides the opportunity to find alternative fabrication strategies of gold-peptide composite nanomaterials. In this study, we used a facile strategy to synthesize the gold nanoparticles via a green and simple approach where they show self-alignment on the assembled nanofibers of ultrashort oligopeptides as a composite material. A photochemical reduction method is used, which does not require any external chemical reagents for the reduction of gold ions, and resultantly makes the gold nanoparticles of size ca. 5 nm under mild UV light exposure. The specific arrangement of gold nanoparticles on the peptide nanofibers may indicate the electrostatic interactions of two components and the interactions with the amino group of the peptide building block. Furthermore, the gold-peptide nanoparticle composites show the ability as a catalyst to degradation of environmental pollutant p-nitrophenol to p-aminophenol, and the reaction rate constant for catalysis is calculated as 0.057 min-1 at a 50-fold dilute sample of 2 mg/mL and 0.72 mM gold concentration in the composites. This colloidal strategy would help researchers to fabricate the metalized bioorganic composites for various biomedical and bio-catalysis applications.

Original languageBritish English
Pages (from-to)2082-2090
Number of pages9
JournalACS Omega
Issue number2
StatePublished - 18 Jan 2022


Dive into the research topics of 'Synthesis and Organization of Gold-Peptide Nanoparticles for Catalytic Activities'. Together they form a unique fingerprint.

Cite this