Syntheses of Lactams by Tandem Reactions

Marta Meazza; Xavier Companyó; Ramon Rios

doi:10.1002/ajoc.201800300

Syntheses of Lactams by Tandem Reactions

Marta Meazza, Xavier Companyó, Ramon Rios

Chemistry

Research output: Contribution to journal › Review article › peer-review

16 Scopus citations

Abstract

Tandem reactions form two or more new bonds, sequentially and in only one step, avoiding the purification of each step and the use of protecting groups, thus making them greener procedures. Lactams are cyclic amides present in numerous natural products and pharmaceuticals, therefore the development of new methodologies for their synthesis attracted the attention of synthetic chemists. The aim of this review is to summarize the last advances, since 2012, in the synthesis of lactams through tandem reactions.

Original language	British English
Pages (from-to)	1934-1956
Number of pages	23
Journal	Asian Journal of Organic Chemistry
Volume	7
Issue number	10
DOIs	https://doi.org/10.1002/ajoc.201800300
State	Published - Oct 2018

Keywords

lactams
natural products
organocatalysis
organometallic
tandem reactions

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10.1002/ajoc.201800300

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abstract = "Tandem reactions form two or more new bonds, sequentially and in only one step, avoiding the purification of each step and the use of protecting groups, thus making them greener procedures. Lactams are cyclic amides present in numerous natural products and pharmaceuticals, therefore the development of new methodologies for their synthesis attracted the attention of synthetic chemists. The aim of this review is to summarize the last advances, since 2012, in the synthesis of lactams through tandem reactions.",

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KW - natural products

KW - organocatalysis

KW - organometallic

KW - tandem reactions

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Syntheses of Lactams by Tandem Reactions

Abstract

Keywords

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