Synergistic Catalysis: Enantioselective Ring Expansion of Vinyl Cyclopropanes Combining Four Catalytic Cycles for the Synthesis of Highly Substituted Spirocyclopentanes Bearing up to Four Stereocenters

Marta Meazza; Ramon Rios

doi:10.1002/chem.201601893

Synergistic Catalysis: Enantioselective Ring Expansion of Vinyl Cyclopropanes Combining Four Catalytic Cycles for the Synthesis of Highly Substituted Spirocyclopentanes Bearing up to Four Stereocenters

Marta Meazza
, Ramon Rios

Chemistry

University of Southampton

Research output: Contribution to journal › Article › peer-review

71 Scopus citations

Abstract

A double synergistic cascade reaction is reported, combining transition metal and amine catalysis. The reaction between vinyl cyclopropanes and enals renders the final cyclopentane derivatives in excellent yields and stereoselectivities.

Original language	British English
Pages (from-to)	9923-9928
Number of pages	6
Journal	Chemistry - A European Journal
Volume	22
Issue number	29
DOIs	https://doi.org/10.1002/chem.201601893
State	Published - 11 Jul 2016

Keywords

cascade reaction
cyclopentanes
enantioselective
palladium
synergistic catalysis

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10.1002/chem.201601893

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title = "Synergistic Catalysis: Enantioselective Ring Expansion of Vinyl Cyclopropanes Combining Four Catalytic Cycles for the Synthesis of Highly Substituted Spirocyclopentanes Bearing up to Four Stereocenters",

abstract = "A double synergistic cascade reaction is reported, combining transition metal and amine catalysis. The reaction between vinyl cyclopropanes and enals renders the final cyclopentane derivatives in excellent yields and stereoselectivities.",

keywords = "cascade reaction, cyclopentanes, enantioselective, palladium, synergistic catalysis",

author = "Marta Meazza and Ramon Rios",

note = "Publisher Copyright: {\textcopyright} 2016 WILEY-VCH Verlag GmbH \& Co. KGaA, Weinheim",

year = "2016",

month = jul,

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doi = "10.1002/chem.201601893",

language = "British English",

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Synergistic Catalysis: Enantioselective Ring Expansion of Vinyl Cyclopropanes Combining Four Catalytic Cycles for the Synthesis of Highly Substituted Spirocyclopentanes Bearing up to Four Stereocenters. / Meazza, Marta; Rios, Ramon.
In: Chemistry - A European Journal, Vol. 22, No. 29, 11.07.2016, p. 9923-9928.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Synergistic Catalysis

T2 - Enantioselective Ring Expansion of Vinyl Cyclopropanes Combining Four Catalytic Cycles for the Synthesis of Highly Substituted Spirocyclopentanes Bearing up to Four Stereocenters

AU - Meazza, Marta

AU - Rios, Ramon

PY - 2016/7/11

Y1 - 2016/7/11

N2 - A double synergistic cascade reaction is reported, combining transition metal and amine catalysis. The reaction between vinyl cyclopropanes and enals renders the final cyclopentane derivatives in excellent yields and stereoselectivities.

AB - A double synergistic cascade reaction is reported, combining transition metal and amine catalysis. The reaction between vinyl cyclopropanes and enals renders the final cyclopentane derivatives in excellent yields and stereoselectivities.

KW - cascade reaction

KW - cyclopentanes

KW - enantioselective

KW - palladium

KW - synergistic catalysis

UR - https://www.scopus.com/pages/publications/84973571078

U2 - 10.1002/chem.201601893

DO - 10.1002/chem.201601893

M3 - Article

AN - SCOPUS:84973571078

SN - 0947-6539

VL - 22

SP - 9923

EP - 9928

JO - Chemistry - A European Journal

JF - Chemistry - A European Journal

IS - 29

ER -

Synergistic Catalysis: Enantioselective Ring Expansion of Vinyl Cyclopropanes Combining Four Catalytic Cycles for the Synthesis of Highly Substituted Spirocyclopentanes Bearing up to Four Stereocenters

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Keywords

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