Synergistic Catalysis: Enantioselective Ring Expansion of Vinyl Cyclopropanes Combining Four Catalytic Cycles for the Synthesis of Highly Substituted Spirocyclopentanes Bearing up to Four Stereocenters

Marta Meazza, Ramon Rios

Research output: Contribution to journalArticlepeer-review

64 Scopus citations

Abstract

A double synergistic cascade reaction is reported, combining transition metal and amine catalysis. The reaction between vinyl cyclopropanes and enals renders the final cyclopentane derivatives in excellent yields and stereoselectivities.

Original languageBritish English
Pages (from-to)9923-9928
Number of pages6
JournalChemistry - A European Journal
Volume22
Issue number29
DOIs
StatePublished - 11 Jul 2016

Keywords

  • cascade reaction
  • cyclopentanes
  • enantioselective
  • palladium
  • synergistic catalysis

Fingerprint

Dive into the research topics of 'Synergistic Catalysis: Enantioselective Ring Expansion of Vinyl Cyclopropanes Combining Four Catalytic Cycles for the Synthesis of Highly Substituted Spirocyclopentanes Bearing up to Four Stereocenters'. Together they form a unique fingerprint.

Cite this