TY - JOUR
T1 - Surface modification and cytotoxicity of Mg-based bio-alloys
T2 - An overview of recent advances
AU - Ali, Murad
AU - Elsherif, Mohamed
AU - Salih, Ahmed E.
AU - Ul-Hamid, Anwar
AU - Hussein, M. A.
AU - Park, Seongjun
AU - Yetisen, Ali K.
AU - Butt, Haider
N1 - Funding Information:
The authors acknowledge Khalifa University of Science and Technology (KUST) for providing the support to conduct this research.
Publisher Copyright:
© 2020 Elsevier B.V.
PY - 2020/6/5
Y1 - 2020/6/5
N2 - The use of magnesium and its alloys for bone implants, cardiovascular stents, and wound closing devices have received considerable attention recently, however, their rapid degradation remains a major concern. Mg-based alloys degrade in the body prior to the completion of their specified healing period. Various biocompatible coatings have been used to overcome this shortcoming and to improve the surface properties such as hardness, corrosion resistance, and biocompatibility. The biocompatible materials used include calcium phosphate (Ca–P), hydroxyapatite (HA), octa calcium phosphate (Octa-Ca-P), metals (Zr, N, Hf, Nd, Zn, Cr, O, Ti), metal oxides (Al2O3, ZrO2, Cr2O3, SiO2, TiO2, Ta2O5, MgO), fluorides, and biopolymers. This paper reviews the surface treatment techniques utilized for Mg and Mg alloys. Additionally, related problems and possible solutions for Mg-based alloys with cytotoxicity are discussed.
AB - The use of magnesium and its alloys for bone implants, cardiovascular stents, and wound closing devices have received considerable attention recently, however, their rapid degradation remains a major concern. Mg-based alloys degrade in the body prior to the completion of their specified healing period. Various biocompatible coatings have been used to overcome this shortcoming and to improve the surface properties such as hardness, corrosion resistance, and biocompatibility. The biocompatible materials used include calcium phosphate (Ca–P), hydroxyapatite (HA), octa calcium phosphate (Octa-Ca-P), metals (Zr, N, Hf, Nd, Zn, Cr, O, Ti), metal oxides (Al2O3, ZrO2, Cr2O3, SiO2, TiO2, Ta2O5, MgO), fluorides, and biopolymers. This paper reviews the surface treatment techniques utilized for Mg and Mg alloys. Additionally, related problems and possible solutions for Mg-based alloys with cytotoxicity are discussed.
KW - Biocompatibility
KW - Biomedical applications
KW - Coating
KW - Corrosion
KW - Magnesium
UR - http://www.scopus.com/inward/record.url?scp=85078840609&partnerID=8YFLogxK
U2 - 10.1016/j.jallcom.2020.154140
DO - 10.1016/j.jallcom.2020.154140
M3 - Review article
AN - SCOPUS:85078840609
SN - 0925-8388
VL - 825
JO - Journal of Alloys and Compounds
JF - Journal of Alloys and Compounds
M1 - 154140
ER -