TY - JOUR
T1 - Supercritical carbon dioxide extraction of plant phytochemicals for biological and environmental applications – A review
AU - Arumugham, Thanigaivelan
AU - K, Rambabu
AU - Hasan, Shadi W.
AU - Show, Pau Loke
AU - Rinklebe, Jörg
AU - Banat, Fawzi
N1 - Funding Information:
The authors are grateful to Khalifa University of Science & Technology for their research project grant, Competitive Internal Research Award 2019 (Project grant: CIRA-2019-028 ).
Publisher Copyright:
© 2021
PY - 2021/5
Y1 - 2021/5
N2 - Recently, supercritical fluid CO2 extraction (SFE) has emerged as a promising and pervasive technology over conventional extraction techniques for various applications, especially for bioactive compounds extraction and environmental pollutants removal. In this context, temperature and pressure regulate the solvent density and thereby effects the yield, selectivity, and biological/therapeutic properties of the extracted components. However, the nature of plant matrices primarily determines the extraction mechanism based on either density or vapor pressure. The present review aims to cover the recent research and developments of SFE technique in the extraction of bioactive plant phytochemicals with high antioxidant, antibacterial, antimalarial, and anti-inflammatory activities, influencing parameters, process conditions, the investigations for improving the yield and selectivity. In another portion of this review focuses on the ecotoxicology and toxic metal recovery applications. Nonpolar properties of Sc-CO2 create strong solvent strength via distinct intermolecular interaction forces with micro-pollutants and toxic metal complexes. This results in efficient removal of these contaminants and makes SFE technology as a superior alternative for conventional solvent-based treatment methods. Moreover, a compelling assessment on the therapeutic, functional, and solvent properties of SFE is rarely focused, and hence this review would add significant value to the SFE based research studies. Furthermore, we mention the limitations and potential of future perspectives related to SFE applications.
AB - Recently, supercritical fluid CO2 extraction (SFE) has emerged as a promising and pervasive technology over conventional extraction techniques for various applications, especially for bioactive compounds extraction and environmental pollutants removal. In this context, temperature and pressure regulate the solvent density and thereby effects the yield, selectivity, and biological/therapeutic properties of the extracted components. However, the nature of plant matrices primarily determines the extraction mechanism based on either density or vapor pressure. The present review aims to cover the recent research and developments of SFE technique in the extraction of bioactive plant phytochemicals with high antioxidant, antibacterial, antimalarial, and anti-inflammatory activities, influencing parameters, process conditions, the investigations for improving the yield and selectivity. In another portion of this review focuses on the ecotoxicology and toxic metal recovery applications. Nonpolar properties of Sc-CO2 create strong solvent strength via distinct intermolecular interaction forces with micro-pollutants and toxic metal complexes. This results in efficient removal of these contaminants and makes SFE technology as a superior alternative for conventional solvent-based treatment methods. Moreover, a compelling assessment on the therapeutic, functional, and solvent properties of SFE is rarely focused, and hence this review would add significant value to the SFE based research studies. Furthermore, we mention the limitations and potential of future perspectives related to SFE applications.
KW - Antioxidant activity
KW - Bioactive compounds
KW - Environmental applications
KW - Supercritical CO extraction
KW - Therapeutic properties
UR - http://www.scopus.com/inward/record.url?scp=85099246062&partnerID=8YFLogxK
U2 - 10.1016/j.chemosphere.2020.129525
DO - 10.1016/j.chemosphere.2020.129525
M3 - Article
C2 - 33445028
AN - SCOPUS:85099246062
SN - 0045-6535
VL - 271
JO - Chemosphere
JF - Chemosphere
M1 - 129525
ER -
