Somatostatin immunoreactivity in bone and joint tissues

Adlan M. Elhassan; Abdu Adem; K. Hultenby; J. U. Lindgren

doi:10.1097/00001756-199808030-00027

Somatostatin immunoreactivity in bone and joint tissues

Adlan M. Elhassan, Abdu Adem, K. Hultenby, J. U. Lindgren

College of Medicine and Health Sciences

Huddinge Hospital

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Using immunoelectron microscopy we have investigated the presence of somatostatin in normal bone and joint tissues. We observed somatostatin labeling in the myelinated nerve fibers of the periosteum, the bone marrow cells and in the mature bone matrix but only slightly in the synovial cells. Quantification of somatostatin in bone tissue by radioimmunoassay showed highest levels in bone marrow followed by periosteum and cortical bone. These findings suggest a role for somatostatin in bone and joint physiology.

Original language	British English
Pages (from-to)	2573-2575
Number of pages	3
Journal	NeuroReport
Volume	9
Issue number	11
DOIs	https://doi.org/10.1097/00001756-199808030-00027
State	Published - 3 Aug 1998

Keywords

Bone
Myelinated nerve
Periosteum
Somatostatin

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AU - Elhassan, Adlan M.

AU - Adem, Abdu

AU - Hultenby, K.

AU - Lindgren, J. U.

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N2 - Using immunoelectron microscopy we have investigated the presence of somatostatin in normal bone and joint tissues. We observed somatostatin labeling in the myelinated nerve fibers of the periosteum, the bone marrow cells and in the mature bone matrix but only slightly in the synovial cells. Quantification of somatostatin in bone tissue by radioimmunoassay showed highest levels in bone marrow followed by periosteum and cortical bone. These findings suggest a role for somatostatin in bone and joint physiology.

AB - Using immunoelectron microscopy we have investigated the presence of somatostatin in normal bone and joint tissues. We observed somatostatin labeling in the myelinated nerve fibers of the periosteum, the bone marrow cells and in the mature bone matrix but only slightly in the synovial cells. Quantification of somatostatin in bone tissue by radioimmunoassay showed highest levels in bone marrow followed by periosteum and cortical bone. These findings suggest a role for somatostatin in bone and joint physiology.

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Somatostatin immunoreactivity in bone and joint tissues

Abstract

Keywords

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