Simultaneous electrochemical determination of dopamine, uric acid, tryptophan on electropolymerized aminothiazole and gold nanoparticles modified carbon nanotubes modified electrode

Cheng Yu Yang, Shen Ming Chen, Selvakumar Palanisamy

    Research output: Contribution to journalArticlepeer-review

    11 Scopus citations

    Abstract

    In the present work, a multifunctional biosensor was developed for the simultaneous determination of dopamine (DA), uric acid (UA) and tryptophan (Try) using 2-amino-thiazole (AT)/gold nanoparticles (AuNPs) functionalized multiwalled carbon nanotubes (f-MWCNT) modified electrode. The f-MWCNT/AuNPs-AT composite modified glassy carbon electrode (GCE) was prepared by electrodeposition of AT and followed by electrodeposition of AuNPs and drop casting of f-MWCNT on GCE. The formation of the composite was confirmed by atomic force microscopy, scanning electron microscopy and electrochemical studies. The f-MWCNT/AuNPs-AT modified GCE exhibits good electrocatalytic ability for the simultaneous determination of DA, UA and Try. Cyclic voltammetry and linear sweep voltammetry were used for simultaneous and selective determination of DA, UA and Try. Moreover, the modified electrode also provides good sensitivity and selectivity for the determination of DA, UA and Try.

    Original languageBritish English
    Pages (from-to)2638-2649
    Number of pages12
    JournalInternational Journal of Electrochemical Science
    Volume11
    Issue number4
    DOIs
    StatePublished - 1 Apr 2016

    Keywords

    • Carbon nanotubes
    • Dopamine
    • Electrocatalysis
    • Gold nanoparticles
    • Multifunctional biosensor
    • Tryptophan
    • Uric acid

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