Silicon-based biosensor

Sandeep Arya, Anoop Singh, Asha Sharma, Vinay Gupta

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Scopus citations

Abstract

Silicon-based hybrid nanoparticles have gained much attention because of their extensive biomedical applications. The superiority of the silicon-based hybrid nanoparticles over the other hybrid nanoparticles lies in their excellent barrier properties, light weight, and reinforcement of mechanical performance. The hybrid nanoparticles of silicon also have enhanced biological properties, and hence they can be used as biosensors. The biosensor is an integrated device that provides the specific quantitative analytical information with the help of a bioreceptor. Due to the highly selective nature of the recognition element toward the target analyte, the biosensor shows better results in comparison with the chemical sensors. The high specificity, reusability, sensitivity, and compact size of the biosensor are the enhanced properties of the sensing device, which makes the biosensor an attractive alternative to the conventionally used techniques. An optical sensor made through the utilization of hybrid nanoparticles of silicon has been already reported for the sensing of virus, antibody, DNA, and other small analytes.

Original languageBritish English
Title of host publicationSilicon-Based Hybrid Nanoparticles
Subtitle of host publicationFundamentals, Properties, and Applications
PublisherElsevier
Pages247-267
Number of pages21
ISBN (Electronic)9780128240076
DOIs
StatePublished - 1 Jan 2021

Keywords

  • Analyte
  • Biosensor
  • Hybrid nanoparticles
  • Sensing device

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