Selective induction of glutathione S-transferase D in rat testis by phenobarbital

D. Sheehan, C. M. Ryle, T. J. Mantle

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9 Scopus citations

Abstract

Testis cytosol is shown to contain the Yb2Yb2-homodimer glutathione S-transferase D in addition to the previously described glutathione S-transferases A(Yb1Yb1) and C (Yb1Yb2). Treatment of rats with phenobarbital induces the level of glutathione S-transferase D in testis with no increase in the activities of glutathione S-transferases A and C. This result indicates a specific induction of the Yb2 subunit in testis, in contrast with the situation in rat liver, where phenobarbital specifically induces the Yb1 subunit.

Original languageBritish English
Pages (from-to)687-688
Number of pages2
JournalBiochemical Journal
Volume219
Issue number2
DOIs
StatePublished - 1984

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