@inbook{a8828d4cbaf04c2f988f212bdd9ba441,
title = "RNA Methylation in the Control of Stem Cell Activity and Epidermal Differentiation",
abstract = "Abundant non-coding RNAs including transfer and ribosomal RNAs are extensively modified, and some of these chemical modifications such as methylation also occur in regulatory non-coding RNAs and coding RNAs. The deposition of a methyl mark onto adenosines (m6A) and cytosines (m5C) is highly conserved and both have emerged as important modifications regulating fundamental cellular processes in developing and adult tissues in mammals. In this chapter, we will review the broad roles of m6A and m5C post-transcriptional methylation in regulating stem cell fate and differentiation processes in skin and other adult tissues, and we will discuss the existence of an additional layer of protein expression control through epigenetic regulation at the RNA level.",
author = "Sajini, \{Abdulrahim A.\} and Michaela Frye",
note = "Publisher Copyright: {\textcopyright} Springer International Publishing AG, part of Springer Nature 2018.",
year = "2018",
doi = "10.1007/978-3-319-16769-5\_9",
language = "British English",
series = "Stem Cell Biology and Regenerative Medicine",
publisher = "Springer Nature",
pages = "215--229",
booktitle = "Stem Cell Biology and Regenerative Medicine",
address = "United Kingdom",
}