Relationship between Angiotensin converting enzyme gene and cardiac autonomic neuropathy among Australian population

Ahmad Shaker Abdalrada, Jemal H. Abawajy, Morshed U. Chowdhury, Sutharshan Rajasegarar, Tahsien Al-Quraishi, Herbert F. Jelinek

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

Angiotensin Converting Enzyme (ACE) gene considers a risk factor for many pathologies such as hypertensive, and diabetic nephropathy. The objective of this study was to investigate the role of ACE genotype with Cardiovascular Autonomic Neuropathy (CAN). We used a data set for 299 participants with and without CAN, as well as with different ACE genotype. Various statistical tests have been considered. Logistic regression was applied to demonstrate the size effect of each predictor. The results revealed, there was no significant different between ACE genotype in the patients with and without CAN. Logistic regression demonstrated only Ewing battery tests as an effective predictive factors. Our investigation found ACE genotype was not a risk factor in Cardiovascular Autonomic Neuropathy in the population of our study.

Original languageBritish English
Title of host publicationRecent Advances on Soft Computing and Data Mining - Proceedings of the 3rd International Conference on Soft Computing and Data Mining SCDM 2018
EditorsJemal H. Abawajy, Rozaida Ghazali, Mustafa Mat Deris, Nazri Mohd Nawi
PublisherSpringer Verlag
Pages135-146
Number of pages12
ISBN (Print)9783319725499
DOIs
StatePublished - 2018
Event3rd International Conference on Soft Computing and Data Mining, SCDM 2018 - Johor, Malaysia
Duration: 6 Feb 20188 Feb 2018

Publication series

NameAdvances in Intelligent Systems and Computing
Volume700
ISSN (Print)2194-5357

Conference

Conference3rd International Conference on Soft Computing and Data Mining, SCDM 2018
Country/TerritoryMalaysia
CityJohor
Period6/02/188/02/18

Keywords

  • Angiotensin converting enzyme (ACE) gene
  • Cardiovascular autonomic neuropathy (CAN)
  • Logistic regression

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