Raman spectroscopy for detection of stretched DNAs on superhydrophobic surfaces

M. Marini; G. Das; R. La Rocca; F. Gentile; T. Limongi; S. Santoriello; A. Scarpellini; E. Di Fabrizio

doi:10.1016/j.mee.2014.04.008

Raman spectroscopy for detection of stretched DNAs on superhydrophobic surfaces

M. Marini, G. Das, R. La Rocca, F. Gentile, T. Limongi, S. Santoriello, A. Scarpellini, E. Di Fabrizio

Physics

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

A novel approach for the study of low concentrated DNAs (60 pM) using microRaman spectroscopy is reported. A superhydrophobic substrate with array of microPillars is fabricated over which the sample was drop casted. The substrate concentrates the molecules in a very small area with higher molecular density, enabling to carry out the microRaman measurements. Two different DNAs (single strand and double strand) were used to investigate through Raman technique. A spectral Raman difference was found to distinguish the ssDNA and dsDNAs. The approach can be of interest for a wide variety of applications ranging from biological materials interactions characterization to the biomedical field.

Original language	British English
Pages (from-to)	151-154
Number of pages	4
Journal	Microelectronic Engineering
Volume	119
DOIs	https://doi.org/10.1016/j.mee.2014.04.008
State	Published - 1 May 2014

Keywords

microPillars
Nucleic acids
Raman spectroscopy
Superhydrophobicity
Suspended

Access to Document

10.1016/j.mee.2014.04.008

Cite this

@article{02fe17a865bf4408826ef9e4e451a8bd,

title = "Raman spectroscopy for detection of stretched DNAs on superhydrophobic surfaces",

abstract = "A novel approach for the study of low concentrated DNAs (60 pM) using microRaman spectroscopy is reported. A superhydrophobic substrate with array of microPillars is fabricated over which the sample was drop casted. The substrate concentrates the molecules in a very small area with higher molecular density, enabling to carry out the microRaman measurements. Two different DNAs (single strand and double strand) were used to investigate through Raman technique. A spectral Raman difference was found to distinguish the ssDNA and dsDNAs. The approach can be of interest for a wide variety of applications ranging from biological materials interactions characterization to the biomedical field.",

keywords = "microPillars, Nucleic acids, Raman spectroscopy, Superhydrophobicity, Suspended",

author = "M. Marini and G. Das and {La Rocca}, R. and F. Gentile and T. Limongi and S. Santoriello and A. Scarpellini and {Di Fabrizio}, E.",

year = "2014",

month = may,

day = "1",

doi = "10.1016/j.mee.2014.04.008",

language = "British English",

volume = "119",

pages = "151--154",

journal = "Microelectronic Engineering",

issn = "0167-9317",

publisher = "Elsevier B.V.",

}

TY - JOUR

T1 - Raman spectroscopy for detection of stretched DNAs on superhydrophobic surfaces

AU - Marini, M.

AU - Das, G.

AU - La Rocca, R.

AU - Gentile, F.

AU - Limongi, T.

AU - Santoriello, S.

AU - Scarpellini, A.

AU - Di Fabrizio, E.

PY - 2014/5/1

Y1 - 2014/5/1

N2 - A novel approach for the study of low concentrated DNAs (60 pM) using microRaman spectroscopy is reported. A superhydrophobic substrate with array of microPillars is fabricated over which the sample was drop casted. The substrate concentrates the molecules in a very small area with higher molecular density, enabling to carry out the microRaman measurements. Two different DNAs (single strand and double strand) were used to investigate through Raman technique. A spectral Raman difference was found to distinguish the ssDNA and dsDNAs. The approach can be of interest for a wide variety of applications ranging from biological materials interactions characterization to the biomedical field.

AB - A novel approach for the study of low concentrated DNAs (60 pM) using microRaman spectroscopy is reported. A superhydrophobic substrate with array of microPillars is fabricated over which the sample was drop casted. The substrate concentrates the molecules in a very small area with higher molecular density, enabling to carry out the microRaman measurements. Two different DNAs (single strand and double strand) were used to investigate through Raman technique. A spectral Raman difference was found to distinguish the ssDNA and dsDNAs. The approach can be of interest for a wide variety of applications ranging from biological materials interactions characterization to the biomedical field.

KW - microPillars

KW - Nucleic acids

KW - Raman spectroscopy

KW - Superhydrophobicity

KW - Suspended

UR - http://www.scopus.com/inward/record.url?scp=84899679684&partnerID=8YFLogxK

U2 - 10.1016/j.mee.2014.04.008

DO - 10.1016/j.mee.2014.04.008

M3 - Article

AN - SCOPUS:84899679684

SN - 0167-9317

VL - 119

SP - 151

EP - 154

JO - Microelectronic Engineering

JF - Microelectronic Engineering

ER -

Raman spectroscopy for detection of stretched DNAs on superhydrophobic surfaces

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this