Raman spectroscopy for detection of stretched DNAs on superhydrophobic surfaces

M. Marini, G. Das, R. La Rocca, F. Gentile, T. Limongi, S. Santoriello, A. Scarpellini, E. Di Fabrizio

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


A novel approach for the study of low concentrated DNAs (60 pM) using microRaman spectroscopy is reported. A superhydrophobic substrate with array of microPillars is fabricated over which the sample was drop casted. The substrate concentrates the molecules in a very small area with higher molecular density, enabling to carry out the microRaman measurements. Two different DNAs (single strand and double strand) were used to investigate through Raman technique. A spectral Raman difference was found to distinguish the ssDNA and dsDNAs. The approach can be of interest for a wide variety of applications ranging from biological materials interactions characterization to the biomedical field.

Original languageBritish English
Pages (from-to)151-154
Number of pages4
JournalMicroelectronic Engineering
StatePublished - 1 May 2014


  • microPillars
  • Nucleic acids
  • Raman spectroscopy
  • Superhydrophobicity
  • Suspended


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