Preparation of highly stable fullerene C60 decorated graphene oxide nanocomposite and its sensitive electrochemical detection of dopamine in rat brain and pharmaceutical samples

Balamurugan Thirumalraj, Selvakumar Palanisamy, Shen Ming Chen, Bih Show Lou

    Research output: Contribution to journalArticlepeer-review

    62 Scopus citations

    Abstract

    The research community has continuously paid much attention on the preparation of hybrid of carbon nanomaterials owing to combine their unique properties. Herein, we report the preparation of highly stable fullerene C60 (C60) wrapped graphene oxide (GO) nanocomposite by using a simple sonication method. The fabricated GO-C60 nanocomposite modified glassy carbon electrode shows a good sensitivity and lower oxidation overpotential towards dopamine (DA) than that of pristine GO and C60. The fabricated sensor detects the DA in the linear response range of 0.02-73.5μM. The limit of detection is estimated to be 0.008μM based on 3σ with a sensitivity of 4.23μAμM-1cm-2. The fabricated sensor also exhibits other features such as good selectivity, stability, reproducibility and repeatability. The proposed sensor exhibits good practicality towards the detection of DA in rat brain and commercial DA injection samples.

    Original languageBritish English
    Pages (from-to)375-381
    Number of pages7
    JournalJournal of Colloid and Interface Science
    Volume462
    DOIs
    StatePublished - 15 Jan 2016

    Keywords

    • Differential pulse voltammetry
    • Dopamine
    • Electrochemical sensor
    • Fullerene C60
    • Graphene oxide
    • Nanocomposite

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