TY - GEN
T1 - Perturbation in parasympathetic nervous system activity affects temporal structure of Poincaré plot
AU - Karmakar, Chandan
AU - Khandoker, Ahsan
AU - Palaniswami, Marimuthu
PY - 2010
Y1 - 2010
N2 - A novel descriptor (Complex Correlation Measure (CCM)) for measuring the variability in the temporal structure of Poincaré plot has been developed to characterize or distinguish between Poincaré plots with similar shapes. This study was designed to assess the changes in temporal structure of the Poincaré plot using CCM during atropine infusion, 70° head-up tilt and scopolamine administration. The aim of this study was to asses the changes in temporal structure of the Poincaré plot using CCM during atropine infusion (parasympathetic blockade) and transdermal scopolamine patch administration (enhanced parasympathetic activity) phases. The change in CCM values during these autonomic perturbation phases revealed the physiological relevance of the new descriptor. The concordant reduction and enhancement in CCM values with parasympathetic activity indicates that the temporal variability of Poincaré plot is modulated by the parasympathetic activity which correlates with changes in CCM values.
AB - A novel descriptor (Complex Correlation Measure (CCM)) for measuring the variability in the temporal structure of Poincaré plot has been developed to characterize or distinguish between Poincaré plots with similar shapes. This study was designed to assess the changes in temporal structure of the Poincaré plot using CCM during atropine infusion, 70° head-up tilt and scopolamine administration. The aim of this study was to asses the changes in temporal structure of the Poincaré plot using CCM during atropine infusion (parasympathetic blockade) and transdermal scopolamine patch administration (enhanced parasympathetic activity) phases. The change in CCM values during these autonomic perturbation phases revealed the physiological relevance of the new descriptor. The concordant reduction and enhancement in CCM values with parasympathetic activity indicates that the temporal variability of Poincaré plot is modulated by the parasympathetic activity which correlates with changes in CCM values.
UR - http://www.scopus.com/inward/record.url?scp=79953823266&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:79953823266
SN - 9781424473182
T3 - Computing in Cardiology
SP - 597
EP - 600
BT - Computing in Cardiology 2010, CinC 2010
T2 - Computing in Cardiology 2010, CinC 2010
Y2 - 26 September 2010 through 29 September 2010
ER -