Abstract
A regiospecific, highly chemo-, diastereo-, and enantioselective one-pot catalytic cascade synthesis of cycloheptane derivatives is presented. In this chiralamine-catalyzed asymmetric process, six new bonds and five new stereocenters were formed with excellent stereocontrol (> 25:1 d.r. and 98- >99 ee).
Original language | British English |
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Pages (from-to) | 2693-2698 |
Number of pages | 6 |
Journal | Chemistry - A European Journal |
Volume | 14 |
Issue number | 9 |
DOIs | |
State | Published - 17 Mar 2008 |
Keywords
- Asymmetric catalysis
- Cascade reaction
- Chiral amines
- Cycloaddition
- Cycloheptane derivatives