Nanotechnology for cancer drug design, delivery, and theranostics applications

Manzar Abbas, Muhammad Ovais, Sudip Mukherjee, Arbab Ali, Muhammad Hanif, Chunying Chen

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

3 Scopus citations

Abstract

Cancer is the most threatening disease for humans worldwide. While conventional treatment modalities have limitations and result in adverse side effects, nanotechnology offers a new avenue in the development of cancer nanomedicine. Herein, we discuss the state-of-the-art principles in the design and discovery of nanomaterials for clinical use in the diagnosis and treatment of cancer. The potential physical parameters of nanomaterials such as size, polydispersity, surface potential, and stability that play a critical role in precise delivery to the targeted sites of tumors are described. Furthermore, precision cancer nano therapy is detailed with the evolving role of multifunctional nanoparticles for cancer targeting. Absorption, distribution, metabolism, and excretion (ADME) are key processes that represent the biomedical properties and toxicity profile of nanomaterials are also discussed. Improving the theranostic efficiency of nanomaterials in clinical settings needs intellectual approaches with clear understanding.

Original languageBritish English
Title of host publicationBiogenic Nanoparticles for Cancer Theranostics
PublisherElsevier
Pages1-26
Number of pages26
ISBN (Electronic)9780128214671
DOIs
StatePublished - 1 Jan 2021

Keywords

  • Cancer
  • Drug design and delivery
  • Nanomedicine
  • Nanotechnology
  • Theranostics

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