MOMSense: Metal-Oxide-Metal Elementary Glucose Sensor

Heba Abunahla; Baker Mohammad; Anas Alazzam; Maguy Abi Jaoude; Mahmoud Al-Qutayri; Sabina Abdul Hadi; Said F. Al-Sarawi

doi:10.1038/s41598-019-41892-w

MOMSense: Metal-Oxide-Metal Elementary Glucose Sensor

Heba Abunahla, Baker Mohammad, Anas Alazzam, Maguy Abi Jaoude, Mahmoud Al-Qutayri, Sabina Abdul Hadi, Said F. Al-Sarawi

University of Adelaide

Research output: Contribution to journal › Article › peer-review

42 Scopus citations

Abstract

In this paper, we present a novel Pt/CuO/Pt metal-oxide-metal (MOM) glucose sensor. The devices are fabricated using a simple, low-cost standard photolithography process. The unique planar structure of the device provides a large electrochemically active surface area, which acts as a nonenzymatic reservoir for glucose oxidation. The sensor has a linear sensing range between 2.2 mM and 10 mM of glucose concentration, which covers the blood glucose levels for an adult human. The distinguishing property of this sensor is its ability to measure glucose at neutral pH conditions (i.e. pH = 7). Furthermore, the dilution step commonly needed for CuO-based nonenzymatic electrochemical sensors to achieve an alkaline medium, which is essential to perform redox reactions in the absence of glucose oxidase, is eliminated, resulting in a lower-cost and more compact device.

Original language	British English
Article number	5524
Journal	Scientific Reports
Volume	9
Issue number	1
DOIs	https://doi.org/10.1038/s41598-019-41892-w
State	Published - 1 Dec 2019

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title = "MOMSense: Metal-Oxide-Metal Elementary Glucose Sensor",

abstract = "In this paper, we present a novel Pt/CuO/Pt metal-oxide-metal (MOM) glucose sensor. The devices are fabricated using a simple, low-cost standard photolithography process. The unique planar structure of the device provides a large electrochemically active surface area, which acts as a nonenzymatic reservoir for glucose oxidation. The sensor has a linear sensing range between 2.2 mM and 10 mM of glucose concentration, which covers the blood glucose levels for an adult human. The distinguishing property of this sensor is its ability to measure glucose at neutral pH conditions (i.e. pH = 7). Furthermore, the dilution step commonly needed for CuO-based nonenzymatic electrochemical sensors to achieve an alkaline medium, which is essential to perform redox reactions in the absence of glucose oxidase, is eliminated, resulting in a lower-cost and more compact device.",

author = "Heba Abunahla and Baker Mohammad and Anas Alazzam and Jaoude, {Maguy Abi} and Mahmoud Al-Qutayri and {Abdul Hadi}, Sabina and Al-Sarawi, {Said F.}",

note = "Funding Information: This research was supported by Khalifa University KUSTAR-KUIRF L2 internal research grant and System on Chip Center RC2-2018-20. Publisher Copyright: {\textcopyright} 2019, The Author(s).",

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doi = "10.1038/s41598-019-41892-w",

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AU - Abunahla, Heba

AU - Mohammad, Baker

AU - Alazzam, Anas

AU - Jaoude, Maguy Abi

AU - Al-Qutayri, Mahmoud

AU - Abdul Hadi, Sabina

AU - Al-Sarawi, Said F.

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AB - In this paper, we present a novel Pt/CuO/Pt metal-oxide-metal (MOM) glucose sensor. The devices are fabricated using a simple, low-cost standard photolithography process. The unique planar structure of the device provides a large electrochemically active surface area, which acts as a nonenzymatic reservoir for glucose oxidation. The sensor has a linear sensing range between 2.2 mM and 10 mM of glucose concentration, which covers the blood glucose levels for an adult human. The distinguishing property of this sensor is its ability to measure glucose at neutral pH conditions (i.e. pH = 7). Furthermore, the dilution step commonly needed for CuO-based nonenzymatic electrochemical sensors to achieve an alkaline medium, which is essential to perform redox reactions in the absence of glucose oxidase, is eliminated, resulting in a lower-cost and more compact device.

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MOMSense: Metal-Oxide-Metal Elementary Glucose Sensor

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