Modeling and simulation of the multiphase flow involving magnetophoresis-based microfluidic systems

Saud A. Khashan, Anas Alazzam, Bobby Mathew

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

In this study, we use the Lagrangian-Eulerian model, usually termed as Discrete Particle Model(DPM), and the Eulerian mixture model to numerically simulate the magnetophoresis-based separation of magnetic beads in a microfluidic system. The separation is based on High Gradient Magnetic Separation (HGMS) principle. A comparative abebment of both computational models was conducted. Mixture model provides a solution similar to that obtained using the DPM but with reduced computational time. However, the fidelity of mixture model can be attained only by the proper modeling of the slip velocity between the particle and the carrier fluid. For both of DPM and mixture approaches, the appropriate constitutive physics models for drag, lift, slip were resolved.

Original languageBritish English
Title of host publicationSmart Sensors, Actuators, and MEMS VII; and Cyber Physical Systems
EditorsJose L. Sanchez-Rojas, Riccardo Brama
PublisherSPIE
ISBN (Electronic)9781628416398
DOIs
StatePublished - 2015
EventSmart Sensors, Actuators, and MEMS VII; and Cyber Physical Systems - Barcelona, Spain
Duration: 4 May 20156 May 2015

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume9517
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X

Conference

ConferenceSmart Sensors, Actuators, and MEMS VII; and Cyber Physical Systems
Country/TerritorySpain
CityBarcelona
Period4/05/156/05/15

Keywords

  • Biomagnetic Fluid Dynamics
  • Cell Separation
  • Discrete Particle Model
  • Magnetic Beads
  • Magnetophoresis
  • Microfluidics
  • Mixture Model

Fingerprint

Dive into the research topics of 'Modeling and simulation of the multiphase flow involving magnetophoresis-based microfluidic systems'. Together they form a unique fingerprint.

Cite this