TY - JOUR
T1 - Metal accumulation, biochemical and behavioral responses on the Mediterranean clams Ruditapes decussatus exposed to two photocatalyst nanocomposites (TiO2 NPs and AuTiO2NPs)
AU - Saidani, Wiem
AU - Sellami, Badreddine
AU - Khazri, Abdelhafidh
AU - Mezni, Amine
AU - Dellali, Mouhamed
AU - Joubert, Olivier
AU - Sheehan, David
AU - Beyrem, Hamouda
N1 - Funding Information:
This study was partly supported by Faculty of Sciences of Bizerte, University of Carthage and Tunis International Center for Environmental Technologies, Tunisia . The authors are grateful to the team at the National Institute of Marine Sciences and Technologies, the Department of Chemistry – Faculty of Science, Taif University, Taif, Saudi Arabia and Institut Jean Lamour, UMR 7198, Université de Lorraine, CNRS, IJL, F-54000 Nancy, France and Khalifa University of Science and Technology for their assistance and support.
Publisher Copyright:
© 2019 Elsevier B.V.
PY - 2019/3
Y1 - 2019/3
N2 - Nanoparticle decoration with noble metal represents a promising alternative to improve their photocatalytic and photovoltaic properties. However, toxicity can be influenced by such modification, as the bioavailability of these substances may be influenced. To understand how decoration influences the NP impacts in marine ecosystems, we exposed suspension-feeding clams, Ruditapes decussatus, to two photocatalyst nanocomposites, TiO2 NPs and AuTiO2 NPs, over 2 concentrations, 50 μg L−1and 100 μg L−1, in a laboratory experiment. Accumulation of Au and Ti in gills and digestive gland was noted in clams after exposure to TiO2 NPs and AuTiO2 NPs using inductively coupled plasma optic emission spectroscopy (ICP-OES). TiO2 and AuTiO2 NPs alter the behavior of the clams Ruditapes decussatus by reducing filtration and respiration rates. Furthermore, the highest concentration of TiO2NPs induces an overproduction of H2O2 in gills and digestive gland and NO production only in gills. Superoxide dismutase (SOD), Catalase (CAT), Glutathione-S-transferase (GST) and acetylcholinesterase (AChE) activities were induced in gills and digestives gland in concentration and nanocomposite type dependent manner. Decorated form presented higher Malondialdehyde (MDA) levels in gills and digestive gland than the undecorated form, suggesting different mechanisms of action that may be mediated through oxidative stress. In conclusion, the considered parameters could represent reliable biomarkers for the assessment of NP toxicity on R. decussatus as biological biomonitoring model. In addition, based on the obtained results, nanoparticle decoration influences the toxicity of metal nanoparticles in marine organism.
AB - Nanoparticle decoration with noble metal represents a promising alternative to improve their photocatalytic and photovoltaic properties. However, toxicity can be influenced by such modification, as the bioavailability of these substances may be influenced. To understand how decoration influences the NP impacts in marine ecosystems, we exposed suspension-feeding clams, Ruditapes decussatus, to two photocatalyst nanocomposites, TiO2 NPs and AuTiO2 NPs, over 2 concentrations, 50 μg L−1and 100 μg L−1, in a laboratory experiment. Accumulation of Au and Ti in gills and digestive gland was noted in clams after exposure to TiO2 NPs and AuTiO2 NPs using inductively coupled plasma optic emission spectroscopy (ICP-OES). TiO2 and AuTiO2 NPs alter the behavior of the clams Ruditapes decussatus by reducing filtration and respiration rates. Furthermore, the highest concentration of TiO2NPs induces an overproduction of H2O2 in gills and digestive gland and NO production only in gills. Superoxide dismutase (SOD), Catalase (CAT), Glutathione-S-transferase (GST) and acetylcholinesterase (AChE) activities were induced in gills and digestives gland in concentration and nanocomposite type dependent manner. Decorated form presented higher Malondialdehyde (MDA) levels in gills and digestive gland than the undecorated form, suggesting different mechanisms of action that may be mediated through oxidative stress. In conclusion, the considered parameters could represent reliable biomarkers for the assessment of NP toxicity on R. decussatus as biological biomonitoring model. In addition, based on the obtained results, nanoparticle decoration influences the toxicity of metal nanoparticles in marine organism.
KW - AuTiONPs
KW - Biomarkers
KW - Oxidative stress
KW - Ruditapes decussatus
KW - TiO NPs
UR - http://www.scopus.com/inward/record.url?scp=85059648966&partnerID=8YFLogxK
U2 - 10.1016/j.aquatox.2019.01.003
DO - 10.1016/j.aquatox.2019.01.003
M3 - Article
C2 - 30639746
AN - SCOPUS:85059648966
SN - 0166-445X
VL - 208
SP - 71
EP - 79
JO - Aquatic Toxicology
JF - Aquatic Toxicology
ER -
