Kutane asthenie (Ehlers-Danlos syndrom) bei einem hauskaninchen

F. Iglauer; G. Wilmering; E. Huisinga; M. Wölm; D. E. Lorke

Kutane asthenie (Ehlers-Danlos syndrom) bei einem hauskaninchen

Translated title of the contribution: Cutaneous asthenia (Ehlers-Danlos-like syndrom) in a rabbit

F. Iglauer, G. Wilmering, E. Huisinga, M. Wölm, D. E. Lorke

College of Medicine and Health Sciences

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Cutaneous asthenia is a connective tissue disease primarily of dogs and cats, resembling Ehlers-Danlos syndrome in man. This is a description of the disorder in a rabbit. The one-year-old female animal was presented because of two large gaping wounds of the skin. Clinical examination reveiled a hyperextensible, thin, and fragile skin. The degree of skin extensibility was evaluated by means of a skin extensibility index (SEI: 19,2 %) and compared with those of 4 healthy rabbits (SEI: 8,3 %-14,3 %). Clinical diagnosis was confirmed by histopathological examination of a skin biopsy revelling reduced packing density of collagen fibers. In addition a decreased number of hair follicles was observed. No conclusion could be drawn regarding the etiology, but existing literature strongly suggests a genetic cause (mostly autosomal dominant inheritance) in humans as well as in animals.

Translated title of the contribution	Cutaneous asthenia (Ehlers-Danlos-like syndrom) in a rabbit
Original language	German
Pages (from-to)	500-505
Number of pages	6
Journal	Deutsche Tierarztliche Wochenschrift
Volume	106
Issue number	12
State	Published - Dec 1999

Keywords

Cutaneous asthenia
Ehlers-Danlos syndrome
Rabbit

Cite this

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title = "Kutane asthenie (Ehlers-Danlos syndrom) bei einem hauskaninchen",

abstract = "Cutaneous asthenia is a connective tissue disease primarily of dogs and cats, resembling Ehlers-Danlos syndrome in man. This is a description of the disorder in a rabbit. The one-year-old female animal was presented because of two large gaping wounds of the skin. Clinical examination reveiled a hyperextensible, thin, and fragile skin. The degree of skin extensibility was evaluated by means of a skin extensibility index (SEI: 19,2 %) and compared with those of 4 healthy rabbits (SEI: 8,3 %-14,3 %). Clinical diagnosis was confirmed by histopathological examination of a skin biopsy revelling reduced packing density of collagen fibers. In addition a decreased number of hair follicles was observed. No conclusion could be drawn regarding the etiology, but existing literature strongly suggests a genetic cause (mostly autosomal dominant inheritance) in humans as well as in animals.",

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T1 - Kutane asthenie (Ehlers-Danlos syndrom) bei einem hauskaninchen

AU - Iglauer, F.

AU - Wilmering, G.

AU - Huisinga, E.

AU - Wölm, M.

AU - Lorke, D. E.

PY - 1999/12

Y1 - 1999/12

N2 - Cutaneous asthenia is a connective tissue disease primarily of dogs and cats, resembling Ehlers-Danlos syndrome in man. This is a description of the disorder in a rabbit. The one-year-old female animal was presented because of two large gaping wounds of the skin. Clinical examination reveiled a hyperextensible, thin, and fragile skin. The degree of skin extensibility was evaluated by means of a skin extensibility index (SEI: 19,2 %) and compared with those of 4 healthy rabbits (SEI: 8,3 %-14,3 %). Clinical diagnosis was confirmed by histopathological examination of a skin biopsy revelling reduced packing density of collagen fibers. In addition a decreased number of hair follicles was observed. No conclusion could be drawn regarding the etiology, but existing literature strongly suggests a genetic cause (mostly autosomal dominant inheritance) in humans as well as in animals.

AB - Cutaneous asthenia is a connective tissue disease primarily of dogs and cats, resembling Ehlers-Danlos syndrome in man. This is a description of the disorder in a rabbit. The one-year-old female animal was presented because of two large gaping wounds of the skin. Clinical examination reveiled a hyperextensible, thin, and fragile skin. The degree of skin extensibility was evaluated by means of a skin extensibility index (SEI: 19,2 %) and compared with those of 4 healthy rabbits (SEI: 8,3 %-14,3 %). Clinical diagnosis was confirmed by histopathological examination of a skin biopsy revelling reduced packing density of collagen fibers. In addition a decreased number of hair follicles was observed. No conclusion could be drawn regarding the etiology, but existing literature strongly suggests a genetic cause (mostly autosomal dominant inheritance) in humans as well as in animals.

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KW - Ehlers-Danlos syndrome

KW - Rabbit

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Kutane asthenie (Ehlers-Danlos syndrom) bei einem hauskaninchen

Abstract

Keywords

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