Investigating the beat by beat phase synchronization between maternal and fetal heart rates

Qianqian Wang; Ahsan H. Khandoker; Faezeh Marzbanrad; Kiyoe Funamoto; Rika Sugibayashi; Miyuki Endo; Yoshitaka Kimura; Marimuthu Palaniswami

doi:10.1109/EMBC.2013.6610377

Investigating the beat by beat phase synchronization between maternal and fetal heart rates

Qianqian Wang, Ahsan H. Khandoker, Faezeh Marzbanrad, Kiyoe Funamoto, Rika Sugibayashi, Miyuki Endo, Yoshitaka Kimura, Marimuthu Palaniswami

Biomedical Engineering & Biotechnology

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

6 Scopus citations

Abstract

The development of the fetal cardiovascular system plays a crucial role in fetal health. The evolution of the relationship between fetal and maternal cardiac systems during fetal maturation is a characterizing feature for fetal cardiac development. This paper aims to evaluate this relationship by investigating the beat-to-beat synchronization between fetal and maternal heart rates and its variation at different stages of pregnancy. Synchronization epochs and phase locking patterns are analyzed at certain synchronization ratios (SRs) for three gestational age groups (16-26 weeks, 27-33 weeks, 34-40 weeks). Results show that the normalized synchronization epoch is significantly different for three age groups with the p-value of 6.72 10^-6 and 2.89 10^-4 at SR of 1-2 and 4-5 respectively. The variance of phase locking also shows significant difference for three groups with the p-value less than 10^-7 at four SRs. Results also suggest that synchronization may be the force behind the increase in the maternal heart rate to maintain the fetal development and provide supplies for the fetus. Overall, the findings propose new clinical markers for evaluating the antenatal development.

Original language	British English
Title of host publication	2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	3821-3824
Number of pages	4
ISBN (Print)	9781457702167
DOIs	https://doi.org/10.1109/EMBC.2013.6610377
State	Published - 2013
Event	2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 - Osaka, Japan Duration: 3 Jul 2013 → 7 Jul 2013

Publication series

Name	Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
ISSN (Print)	1557-170X

Conference

Conference	2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
Country/Territory	Japan
City	Osaka
Period	3/07/13 → 7/07/13

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1109/EMBC.2013.6610377

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Wang, Q., Khandoker, A. H., Marzbanrad, F., Funamoto, K., Sugibayashi, R., Endo, M., Kimura, Y., & Palaniswami, M. (2013). Investigating the beat by beat phase synchronization between maternal and fetal heart rates. In 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 (pp. 3821-3824). Article 6610377 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2013.6610377

Wang, Qianqian ; Khandoker, Ahsan H. ; Marzbanrad, Faezeh et al. / Investigating the beat by beat phase synchronization between maternal and fetal heart rates. 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013. Institute of Electrical and Electronics Engineers Inc., 2013. pp. 3821-3824 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

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title = "Investigating the beat by beat phase synchronization between maternal and fetal heart rates",

abstract = "The development of the fetal cardiovascular system plays a crucial role in fetal health. The evolution of the relationship between fetal and maternal cardiac systems during fetal maturation is a characterizing feature for fetal cardiac development. This paper aims to evaluate this relationship by investigating the beat-to-beat synchronization between fetal and maternal heart rates and its variation at different stages of pregnancy. Synchronization epochs and phase locking patterns are analyzed at certain synchronization ratios (SRs) for three gestational age groups (16-26 weeks, 27-33 weeks, 34-40 weeks). Results show that the normalized synchronization epoch is significantly different for three age groups with the p-value of 6.72 10-6 and 2.89 10-4 at SR of 1-2 and 4-5 respectively. The variance of phase locking also shows significant difference for three groups with the p-value less than 10-7 at four SRs. Results also suggest that synchronization may be the force behind the increase in the maternal heart rate to maintain the fetal development and provide supplies for the fetus. Overall, the findings propose new clinical markers for evaluating the antenatal development.",

author = "Qianqian Wang and Khandoker, {Ahsan H.} and Faezeh Marzbanrad and Kiyoe Funamoto and Rika Sugibayashi and Miyuki Endo and Yoshitaka Kimura and Marimuthu Palaniswami",

year = "2013",

doi = "10.1109/EMBC.2013.6610377",

language = "British English",

isbn = "9781457702167",

series = "Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS",

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booktitle = "2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013",

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Wang, Q, Khandoker, AH, Marzbanrad, F, Funamoto, K, Sugibayashi, R, Endo, M, Kimura, Y & Palaniswami, M 2013, Investigating the beat by beat phase synchronization between maternal and fetal heart rates. in 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013., 6610377, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, Institute of Electrical and Electronics Engineers Inc., pp. 3821-3824, 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013, Osaka, Japan, 3/07/13. https://doi.org/10.1109/EMBC.2013.6610377

Investigating the beat by beat phase synchronization between maternal and fetal heart rates. / Wang, Qianqian; Khandoker, Ahsan H.; Marzbanrad, Faezeh et al.
2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013. Institute of Electrical and Electronics Engineers Inc., 2013. p. 3821-3824 6610377 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Investigating the beat by beat phase synchronization between maternal and fetal heart rates

AU - Wang, Qianqian

AU - Khandoker, Ahsan H.

AU - Marzbanrad, Faezeh

AU - Funamoto, Kiyoe

AU - Sugibayashi, Rika

AU - Endo, Miyuki

AU - Kimura, Yoshitaka

AU - Palaniswami, Marimuthu

PY - 2013

Y1 - 2013

N2 - The development of the fetal cardiovascular system plays a crucial role in fetal health. The evolution of the relationship between fetal and maternal cardiac systems during fetal maturation is a characterizing feature for fetal cardiac development. This paper aims to evaluate this relationship by investigating the beat-to-beat synchronization between fetal and maternal heart rates and its variation at different stages of pregnancy. Synchronization epochs and phase locking patterns are analyzed at certain synchronization ratios (SRs) for three gestational age groups (16-26 weeks, 27-33 weeks, 34-40 weeks). Results show that the normalized synchronization epoch is significantly different for three age groups with the p-value of 6.72 10-6 and 2.89 10-4 at SR of 1-2 and 4-5 respectively. The variance of phase locking also shows significant difference for three groups with the p-value less than 10-7 at four SRs. Results also suggest that synchronization may be the force behind the increase in the maternal heart rate to maintain the fetal development and provide supplies for the fetus. Overall, the findings propose new clinical markers for evaluating the antenatal development.

AB - The development of the fetal cardiovascular system plays a crucial role in fetal health. The evolution of the relationship between fetal and maternal cardiac systems during fetal maturation is a characterizing feature for fetal cardiac development. This paper aims to evaluate this relationship by investigating the beat-to-beat synchronization between fetal and maternal heart rates and its variation at different stages of pregnancy. Synchronization epochs and phase locking patterns are analyzed at certain synchronization ratios (SRs) for three gestational age groups (16-26 weeks, 27-33 weeks, 34-40 weeks). Results show that the normalized synchronization epoch is significantly different for three age groups with the p-value of 6.72 10-6 and 2.89 10-4 at SR of 1-2 and 4-5 respectively. The variance of phase locking also shows significant difference for three groups with the p-value less than 10-7 at four SRs. Results also suggest that synchronization may be the force behind the increase in the maternal heart rate to maintain the fetal development and provide supplies for the fetus. Overall, the findings propose new clinical markers for evaluating the antenatal development.

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U2 - 10.1109/EMBC.2013.6610377

DO - 10.1109/EMBC.2013.6610377

M3 - Conference contribution

C2 - 24110564

AN - SCOPUS:84886548857

SN - 9781457702167

T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS

SP - 3821

EP - 3824

BT - 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013

Y2 - 3 July 2013 through 7 July 2013

ER -

Wang Q, Khandoker AH, Marzbanrad F, Funamoto K, Sugibayashi R, Endo M et al. Investigating the beat by beat phase synchronization between maternal and fetal heart rates. In 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013. Institute of Electrical and Electronics Engineers Inc. 2013. p. 3821-3824. 6610377. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). doi: 10.1109/EMBC.2013.6610377

Investigating the beat by beat phase synchronization between maternal and fetal heart rates

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