Investigating the Association between Resting Heart Rate and Estimated Glomerular Filtration Rate: A UK Biobank study

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Abstract

This study investigates the association of resting heart rate (HR) and HR variability (HRV) with estimated glomerular filtration rate (eGFR) using data from the UK Biobank. To explore this association, the RR interval (RRI) and the standard deviation of RRI (SDRRI) were calculated from 2-minute electrocardiograms (ECGs). The ECG signals were obtained from 1,555 participants who took part in the UK Biobank study. Out of the 1555 participants, 227 had (eGFR <90 m L /min/ 1.73 m2). A multiple linear regression model was developed to predict eGFR from RRI and SDRRI after adjusting for sex, age, and body mass index (BMI). The association between RRI and eGFR was significant, (p<0.05). These findings suggest that HRs could be used to assess kidney function.

Original languageBritish English
Title of host publication2024 13th Conference of the European Study Group on Cardiovascular Oscillations
Subtitle of host publicationPhysiologically-Guided Signal Processing of Cardiovascular and Cerebrovascular Oscillations, ESGCO 2024
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9798350392050
DOIs
StatePublished - 2024
Event13th Conference of the European Study Group on Cardiovascular Oscillations, ESGCO 2024 - Zaragoza, Spain
Duration: 23 Oct 202425 Oct 2024

Publication series

Name2024 13th Conference of the European Study Group on Cardiovascular Oscillations: Physiologically-Guided Signal Processing of Cardiovascular and Cerebrovascular Oscillations, ESGCO 2024

Conference

Conference13th Conference of the European Study Group on Cardiovascular Oscillations, ESGCO 2024
Country/TerritorySpain
CityZaragoza
Period23/10/2425/10/24

Keywords

  • ECG
  • eGFR
  • Heart rate
  • Kidney function

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