Abstract
Accurate and tunable: The title compounds can detect reactive oxygen species (ROS) in cell culture, tissue explants, and for the first time in vivo. The hydrocyanines are synthesized by reduction of the cyanine dyes with NaBH4. They can accurately detect nanomolar levels of ROS, have excellent stability against autoxidation, and have tunable emission wavelengths in the range 560-830 nm. (Figure Presented).
Original language | British English |
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Pages (from-to) | 299-303 |
Number of pages | 5 |
Journal | Angewandte Chemie - International Edition |
Volume | 48 |
Issue number | 2 |
DOIs | |
State | Published - 2 Jan 2009 |
Keywords
- Cyanines
- Fluorescence
- Hydrocyanines
- Reactive oxygen species
- Superoxide