Highly Regio- and Enantioselective Organocatalytic γ-Allylic Alkylation of Quinolines

Marta Meazza, Ramon Rios

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

We report the first synthesis of 2-alkenylquinolines from 2-allylquinolines and α,β-unsaturated aldehydes. The reaction proceeds in a highly regioselective and enantioselective way and shows a broad tolerance of functionalities both in the aromatic ring of the enal and on the quinoline. (Figure presented.).

Original languageBritish English
Pages (from-to)1341-1345
Number of pages5
JournalAdvanced Synthesis and Catalysis
Volume363
Issue number5
DOIs
StatePublished - 2 Mar 2021

Keywords

  • asymmetric catalysis
  • enantioselective
  • organocatalysis
  • quinoline
  • regioselective

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