@article{9798f3a6cab746c885bc8c6626471981,
title = "Highly enantioselective organocatalytic cascade reaction for the synthesis of piperidines and oxazolidines",
abstract = "The synthesis of piperidines and piperidines derivatives in enantiopure fashion has been a challenging goal for organic chemists. In this report we developed a nice cascade reaction for piperidine derivatives based in an amidomalonate Michael addition to enals followed by an intramolecular hemiaminal formation with good yields and enantioselectivities. Moreover we studied the 'in situ' intramolecular cyclization of this hemiaminals with alcohols forming fused piperidine-oxazolidines.",
keywords = "Cascade reaction, Diastereoselective, Enantioselective, Organocatalysis, Paroxetine",
author = "Sylva {\v C}{\'i}halov{\'a} and Guillem Valero and Ji{\v r}{\'i} Schimer and Marek Humpl and Martin Dra{\v c}{\'i}nsk{\'y} and Albert Moyano and Ramon Rios and Jan Vesely",
note = "Funding Information: J.V. gratefully acknowledges the Grant Agency of Czech Republic ( GACR 203/09/P193 ) and Ministry of Education, Youth and Sport (No. MSM0021620857 ), R.R. and A.M. thank to Spanish Ministry of Science and Innovation (MICINN) for financial support (Project AYA2009-13920-C02-02). G.V. is also grateful to MICINN for his pre-doctoral fellowship. J.V. also thanks to Dr. C{\'i}sa{\v r}ov{\'a} for X-ray studies.",
year = "2011",
month = nov,
day = "18",
doi = "10.1016/j.tet.2011.08.079",
language = "British English",
volume = "67",
pages = "8942--8950",
journal = "Tetrahedron",
issn = "0040-4020",
publisher = "Elsevier Ltd",
number = "46",
}