Highly enantioselective fluoromalonate addition to α,β-unsaturated aldehydes

Xavier Companyó, Monika Hejnová, Martin Kamlar, Jan Vesely, Albert Moyano, Ramon Rios

Research output: Contribution to journalArticlepeer-review

58 Scopus citations

Abstract

A highly enantioselective organocatalytic fluoromalonate addition to α,β-unsaturated aldehydes is reported. The reaction is catalyzed by simple and commercially available secondary amines, affording the corresponding 1,4-adducts with high yields and enantioselectivities.

Original languageBritish English
Pages (from-to)5021-5024
Number of pages4
JournalTetrahedron Letters
Volume50
Issue number35
DOIs
StatePublished - 2 Sep 2009

Fingerprint

Dive into the research topics of 'Highly enantioselective fluoromalonate addition to α,β-unsaturated aldehydes'. Together they form a unique fingerprint.

Cite this