Heart rate variability and QT dispersion in a cohort of diabetes patients

Herbert F. Jelinek, Ahsan Khandoker, Marimuthu Palaniswami, Simon McDonald

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

9 Scopus citations

Abstract

Heart rate is dependent on a cycle of depolarization and repolarization of the atria and ventricles that is regulated by intrinsic and extrinsic factors. Inhomogeneity in ventricular repolarization, measured as QT interval dispersion (QTd) is likely to lead to arrhythmia. The role of the autonomic nervous system in the development of this inhomogeneity is still uncertain. Autonomic regulation can be measured using the toneentropy algorithm, which indicates inter-beat interval variation.When a sliding cut-off for QTd was used only the control group had a significant association between QTd and both tone and entropy. This finding suggests that for certain levels of ventricular inhomogeneity, autonomic control becomes more dissociated from intrabeta variation measured by QTd. This may be an early sign of potentially fatal arrhythmia.

Original languageBritish English
Title of host publicationComputing in Cardiology 2010, CinC 2010
Pages613-616
Number of pages4
StatePublished - 2010
EventComputing in Cardiology 2010, CinC 2010 - Belfast, United Kingdom
Duration: 26 Sep 201029 Sep 2010

Publication series

NameComputing in Cardiology
Volume37
ISSN (Print)2325-8861
ISSN (Electronic)2325-887X

Conference

ConferenceComputing in Cardiology 2010, CinC 2010
Country/TerritoryUnited Kingdom
CityBelfast
Period26/09/1029/09/10

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