@inproceedings{8d392aec69284ed79ab19bc07266dd4f,
title = "GOtoGene: A method for determining the functional similarity among gene products",
abstract = "We present in this paper novel techniques that determine the semantic relationships among genes and gene products. We implemented these techniques in a middleware system called GOtoGene, which resides between user application and Gene Ontology database. Given a set S of genes, GOtoGene would return another set S' of genes, where each gene in S' is semantically related to each gene in S. The framework of GOtoGene refines the concept of Lowest Common Ancestor by defining the concept of Semantically Relevant Lowest Common Ancestor using the concept of existence dependency. We evaluated GOtoGene experimentally and compared it with three other methods. Results showed marked improvement.",
keywords = "Gene ontology, Middleware, Semantic similarity",
author = "Kamal Taha",
note = "Publisher Copyright: {\textcopyright} 2012, Australian Computer Society, Inc.",
year = "2012",
language = "British English",
series = "Conferences in Research and Practice in Information Technology Series",
pages = "43--51",
editor = "Yanchang Zhao and Peter Christen and Jiuyong Li and Kennedy, \{Paul J.\}",
booktitle = "Proceedings of the 10th Australasian Data Mining Conference, AusDM 2012",
}