Gold nanoparticles and oxidative stress in Mytilus edulis

S. Tedesco, H. Doyle, G. Redmond, D. Sheehan

Research output: Contribution to journalArticlepeer-review

112 Scopus citations

Abstract

Little is known about potential environmental impact of nanoparticles. Gold nanoparticles can cause unexpected biological responses. Here, Mytilus edulis were exposed (24 h) to gold-citrate nanoparticles (GNP), menadione and both compounds simultaneously (GNP/menadione). Protein ubiquitination and carbonylation were determined in gill, mantle and digestive gland, along with traditional oxidative stress biomarkers; catalase activity and neutral red retention time assay (haemolymph). 2DE gels were performed on gill proteins (menadione; GNP/menadione). Our results reveal that GNP may induce oxidative stress.

Original languageBritish English
Pages (from-to)131-133
Number of pages3
JournalMarine Environmental Research
Volume66
Issue number1
DOIs
StatePublished - Jul 2008

Keywords

  • Carbonylation
  • Gold nanoparticles
  • Mytilus edulis
  • Oxidative stress
  • Proteomics
  • Ubiquitin

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