Finite element modelling of a 3 dimensional dielectrophoretic flow separator device for optimal bioprocessing conditions

H. O. Fatoyinbo, M. P. Hughes

Research output: Contribution to journalConference articlepeer-review

Abstract

Planar 2-dimensional dielectrophoresis electrode geometries are limited in only being capable of handling fluid volumes ranging from pico-litres to hundreds of micro-liters per hour. A 3-dimensional electrode system has been developed capable of handling significantly larger volumes of fluid. Using finite element modeling the electric field distribution within various bore sizes was realized. From these simulations it is possible to optimize bioprocessing factors influencing the performance of a dielectrophoretic separator. Process calculations have shown that flow-rates of 25ml hr -1 or more can be attained for the separation of heterogeneous populations of bio-particles based on their dielectric properties.

Original languageBritish English
Pages (from-to)2587-2590
Number of pages4
JournalAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume26 IV
StatePublished - 2004
EventConference Proceedings - 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2004 - San Francisco, CA, United States
Duration: 1 Sep 20045 Sep 2004

Keywords

  • 3-D modeling
  • Bioprocess
  • Dielectrophoresis

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