Abstract
Liquid biphasic systems can adopt extractive distillation as a method of separation pertaining to a binary feed mixture of similar boiling point components via addition of a mass separating agent. Solvents operate on the principle of selectivity, which induces the feed components to dissolve or disperse to form two immiscible liquid phases that can be separated either in the conventional two-column configuration or a single-column set-up. This chapter covers the topic of the operating principles of extractive distillation, design specifications of the column, and types of solvents that influence the separation efficiency and industrial application of this technology. Further work on potential scale-up and optimization strategies is discussed at the end of this chapter.
Original language | British English |
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Title of host publication | Liquid Biphasic System |
Subtitle of host publication | Fundamentals and Applications in Bioseparation Technology |
Publisher | Elsevier |
Pages | 285-300 |
Number of pages | 16 |
ISBN (Electronic) | 9780128199862 |
DOIs | |
State | Published - 1 Jan 2020 |
Keywords
- Column type
- Design
- Extractive distillation
- Liquid biphasic system
- Mass separating agent