Extractive technologies in liquid biphasic systems: Extractive distillation

Revathy Sankaran, Natalie Fernandez, Tau Chuan Ling, Pau Loke Show

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Liquid biphasic systems can adopt extractive distillation as a method of separation pertaining to a binary feed mixture of similar boiling point components via addition of a mass separating agent. Solvents operate on the principle of selectivity, which induces the feed components to dissolve or disperse to form two immiscible liquid phases that can be separated either in the conventional two-column configuration or a single-column set-up. This chapter covers the topic of the operating principles of extractive distillation, design specifications of the column, and types of solvents that influence the separation efficiency and industrial application of this technology. Further work on potential scale-up and optimization strategies is discussed at the end of this chapter.

Original languageBritish English
Title of host publicationLiquid Biphasic System
Subtitle of host publicationFundamentals and Applications in Bioseparation Technology
Number of pages16
ISBN (Electronic)9780128199862
StatePublished - 1 Jan 2020


  • Column type
  • Design
  • Extractive distillation
  • Liquid biphasic system
  • Mass separating agent


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