Evidence of a role for Th17 cells in the breach of immune tolerance in arthritis

Xinhua Yu, Saleh M. Ibrahim

Research output: Contribution to journalEditorial

3 Scopus citations

Abstract

Th17 cells are thought to play a pathogenic role in various autoimmune diseases. Cytokines secreted by Th17 cells like IL-17, IL-17F and IL-22 have the capacity to mediate a massive inflammatory response. These proinflammatroy cytokines are likely to mediate the pathogenic potential of Th17 cells. Recent evidence suggests a role for Th17 cells in the breach of immune tolerance. This might shed some new light on the pathogenic role of Th17 cells in autoimmunity.

Original languageBritish English
Article number132
JournalArthritis Research and Therapy
Volume13
Issue number5
DOIs
StatePublished - 31 Oct 2011

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