Estimating fetal gestational age using cardiac valve intervals

Faezeh Marzbanrad, Ahsan H. Khandoker, Yoshitaka Kimura, Marimuthu Palaniswami, Gari D. Clifford

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

6 Scopus citations


A new automated method for estimation of the gestational age is presented in this paper based on the intervals between fetal cardiac valve timings and the Q-wave of fetal electrocardiogram (fECG). The intervals were estimated automatically from one-dimensional Doppler Ultrasound and noninvasive fECG. Among the intervals, Isovolumic Contraction Time, Electromechanical Delay Time, Ventricular Filling Time and their interactions were selected in a stepwise regression process. Compared with Crown-Rump Length as gold standard, a mean absolute error of 3.8 weeks was obtained using leave-one-out cross validation. This method also outperformed a fetal heart rate based approach. Since valve intervals reflect the autonomic function, this method provides a novel measure ofthe development of fetal autonomic nervous system that may be growth curve independent.

Original languageBritish English
Title of host publicationComputing in Cardiology Conference, CinC 2016
EditorsAlan Murray
PublisherIEEE Computer Society
Number of pages4
ISBN (Electronic)9781509008964
StatePublished - 1 Mar 2016
Event43rd Computing in Cardiology Conference, CinC 2016 - Vancouver, Canada
Duration: 11 Sep 201614 Sep 2016

Publication series

NameComputing in Cardiology
ISSN (Print)2325-8861
ISSN (Electronic)2325-887X


Conference43rd Computing in Cardiology Conference, CinC 2016


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