@article{750eb883b6174f36a79c520b7fe63f84,
title = "Enhanced expression of immune checkpoint receptors during SARS-CoV-2 viral infection",
abstract = "The immune system is tightly regulated by the activity of stimulatory and inhibitory immune receptors. Using gene expression datasets, Halwani and coworkers showed a pattern of overall upregulation of immune inhibitor receptors on different myeloid and lymphoid cells during SARS-CoV-2 infection. This dysregulation may contribute to the immunopathology and severity of COVID-19.",
keywords = "CEACAM1, COVID-19, immune checkpoint inhibitors, immune inhibitory receptors, influenza A virus, lung autopsies, respiratory viral infection, SARS-CoV-2, sialic acid, SIGLEC10",
author = "{Saheb Sharif-Askari}, Narjes and {Saheb Sharif-Askari}, Fatemeh and Bushra Mdkhana and {Al Heialy}, Saba and Alsafar, {Habiba S.} and Rifat Hamoudi and Qutayba Hamid and Rabih Halwani",
note = "Funding Information: This work was supported by a Tissue Injury and Repair Group (TIR Group) operational grant (code 150317 ), COVID-19 research grants ( CoV19-0307 and CoV19-0308 ), and a seed grant (code 2001090275 ); by a collaborative research grant (code 2001090278 ) to R.H., University of Sharjah, UAE ; by a Sandooq Al Watan Applied Research & Development Grant to R.H. ( SWARD-S20-007 ); by an Al Jalila Foundation Seed Grant ( AJF202019 ); and by the Prince Abdullah Ben Khalid Celiac Disease Research Chair , under the Vice Deanship of Research Chairs, King Saud University, Riyadh, Kingdom of Saudi Arabia . Publisher Copyright: {\textcopyright} 2020 The Authors",
year = "2021",
month = mar,
day = "12",
doi = "10.1016/j.omtm.2020.11.002",
language = "British English",
volume = "20",
pages = "109--121",
journal = "Molecular Therapy - Methods and Clinical Development",
issn = "2329-0501",
publisher = "Cell Press",
}
