TY - JOUR
T1 - Engineering carbon nanotubes for sensitive viral detection
AU - Ovais, Muhammad
AU - You, Min
AU - Ahmad, Jalal
AU - Djellabi, Ridha
AU - Ali, Arbab
AU - Akhtar, Mahmood Hassan
AU - Abbas, Manzar
AU - Chen, Chunying
N1 - Funding Information:
This research was supported by International S&T Cooperation Projects of the Ministry of Science and Technology of China ( 2018YFE0117200 ), the Science Fund for Creative Research Groups of the National Natural Science Foundation of China ( 11621505 ), CAS Key Research Program for Frontier Sciences ( QYZDJ-SSW-SLH022 ), CAS interdisciplinary innovation team, NSFC-BRICS Programme (51861145302) and the Research and Development Project in Key Areas of Guangdong Province ( 2019B090917011 ). M.A acknowledges financial support from the European Union's Horizon 2020 program under grant 839177 (PEPREP).
Publisher Copyright:
© 2022 Elsevier B.V.
PY - 2022/8
Y1 - 2022/8
N2 - Viral infections have been proven a severe threat to human beings, and the pandemic of Coronavirus Disease 2019 (COVID-19) has become a societal health concern, including mental distress and morbidity. Therefore, the early diagnosis and differentiation of viral infections are the prerequisite for curbing the local and global spread of viruses. To this end, carbon nanotubes (CNTs) based virus detection strategies are developed that provide feasible alternatives to conventional diagnostic techniques. Here in this review, an overview of the design and engineering of CNTs-based sensors for virus detection is summarized, followed by the nano-bio interactions used in developing biosensors. Then, we classify the viral sensors into covalently engineered CNTs, non-covalently engineered CNTs, and size-tunable CNTs arrays for viral detection, based on the type of CNTs-based nano-bio interfaces. Finally, the current challenges and prospects of CNTs-based sensors for virus detection are discussed.
AB - Viral infections have been proven a severe threat to human beings, and the pandemic of Coronavirus Disease 2019 (COVID-19) has become a societal health concern, including mental distress and morbidity. Therefore, the early diagnosis and differentiation of viral infections are the prerequisite for curbing the local and global spread of viruses. To this end, carbon nanotubes (CNTs) based virus detection strategies are developed that provide feasible alternatives to conventional diagnostic techniques. Here in this review, an overview of the design and engineering of CNTs-based sensors for virus detection is summarized, followed by the nano-bio interactions used in developing biosensors. Then, we classify the viral sensors into covalently engineered CNTs, non-covalently engineered CNTs, and size-tunable CNTs arrays for viral detection, based on the type of CNTs-based nano-bio interfaces. Finally, the current challenges and prospects of CNTs-based sensors for virus detection are discussed.
KW - Carbon nanotubes engineering
KW - CNTs-based sensors
KW - COVID-19
KW - Nano-bio interactions
KW - Virus detection
UR - http://www.scopus.com/inward/record.url?scp=85129698643&partnerID=8YFLogxK
U2 - 10.1016/j.trac.2022.116659
DO - 10.1016/j.trac.2022.116659
M3 - Review article
AN - SCOPUS:85129698643
SN - 0165-9936
VL - 153
JO - TrAC - Trends in Analytical Chemistry
JF - TrAC - Trends in Analytical Chemistry
M1 - 116659
ER -
