Enantioselective organocatalytic Mannich reactions of ferrocenecarbaldehyde

Guillem Valero, Andrea Nekane Balaguer, Albert Moyano, Ramon Rios

Research output: Contribution to journalArticlepeer-review

38 Scopus citations


The first examples of highly enantioselective organocatalytic Mannich reactions of ferrocenecarbaldehyde are disclosed. The reaction is catalyzed by simple amino acids and gives access to β-arylamino-β-ferrocenylketones in high yields and with up to 99% ee.

Original languageBritish English
Pages (from-to)6559-6562
Number of pages4
JournalTetrahedron Letters
Issue number46
StatePublished - 10 Nov 2008


  • Amines
  • Amino acids
  • Asymmetric catalysis
  • Ferrocenes
  • Mannich reaction
  • Organocatalysis


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