Electrodes functionalized with the 2,2,6,6-tetramethylpiperidinyloxy radical for the waste-free oxidation of alcohols

Electrodes functionalised with the organocatalyst 2,2,6,6-tetramethylpiperidinyloxy (TEMPO) moiety hold great potential for the development of waste-free industrial synthesis of valuable carbonyl compounds using electrons and alcohols as the only reactants. Since the inception of the first active electrode in 1988, a number of different electrodes have been developed to the recent fastest TEMPO-mediated alcohol oxidation process ever reported. In addition to good activity and broad applicability to different substrates, the electrode stability is the crucial factor that will guide the adoption of this eminently clean technology by the fine chemical and pharmaceutical industry. Selective oxidation with electricity only: Electrodes functionalized with the organocatalyst 2,2,6,6-tetramethylpiperidinyloxy (TEMPO) hold great potential for the development of the entirely waste-free industrial synthesis of valuable carbonyl compounds in the fine chemical and pharmaceutical industries.