Abstract
The electrochemical determination of Hydralazine hydrochloride (Hy-Hcl) at preanodised screen printed carbon electrode (PSPCE) has been reported. Preanodisation was carried out by keeping the fixed potential at 2.0 V for 120 s by cyclic voltametry (CV) in pH 7 phosphate buffer solution contain KCl. Scanning electron microscopy and electrochemical impedance spectroscopy were used to characterize the preanodised screen printed carbon electrode (SPCE). The electrochemical determination of (Hy-Hcl) has been examined by linear sweep voltametry. In CV, (Hy-Hcl) has showed more oxidation current at PSPCE when compared with only pristine SPCE. Further, Hy-Hcl has the linear range of detection from 0.1 μM to 29.57 μM with a low detection limit was founded as 0.02 μM. Moreover, Hy-Hcl at PSPCE has exhibited an acceptable reproducibility, repeatability with good sensitivity and storage stability. In addition, as a future prospective this method could be used for accurate detection of Hy-Hcl in pharmaceutical industries.
| Original language | British English |
|---|---|
| Pages (from-to) | 11488-11496 |
| Number of pages | 9 |
| Journal | International Journal of Electrochemical Science |
| Volume | 7 |
| Issue number | 11 |
| State | Published - 2012 |
Keywords
- Cyclic voltametry
- Electrochemical determination
- Hydralazine hydrochloride
- Linear sweep voltametry
- Preanodised Screen printed carbon electrode
- Screen printed carbon electrode
