Electrochemical determination of hydralazine hydrochloride by preanodised screen printed carbon electrode

Srikanth Cheemalapati, Selvakumar Palanisamy, Shen Ming Chen

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    12 Scopus citations


    The electrochemical determination of Hydralazine hydrochloride (Hy-Hcl) at preanodised screen printed carbon electrode (PSPCE) has been reported. Preanodisation was carried out by keeping the fixed potential at 2.0 V for 120 s by cyclic voltametry (CV) in pH 7 phosphate buffer solution contain KCl. Scanning electron microscopy and electrochemical impedance spectroscopy were used to characterize the preanodised screen printed carbon electrode (SPCE). The electrochemical determination of (Hy-Hcl) has been examined by linear sweep voltametry. In CV, (Hy-Hcl) has showed more oxidation current at PSPCE when compared with only pristine SPCE. Further, Hy-Hcl has the linear range of detection from 0.1 μM to 29.57 μM with a low detection limit was founded as 0.02 μM. Moreover, Hy-Hcl at PSPCE has exhibited an acceptable reproducibility, repeatability with good sensitivity and storage stability. In addition, as a future prospective this method could be used for accurate detection of Hy-Hcl in pharmaceutical industries.

    Original languageBritish English
    Pages (from-to)11488-11496
    Number of pages9
    JournalInternational Journal of Electrochemical Science
    Issue number11
    StatePublished - 2012


    • Cyclic voltametry
    • Electrochemical determination
    • Hydralazine hydrochloride
    • Linear sweep voltametry
    • Preanodised Screen printed carbon electrode
    • Screen printed carbon electrode


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